(1R,9S)-12-Phenyl-10,12,14-triaza-tricyclo[7.5.2.0^10,14]hexadec-15-ene-11,13-dione

Base Information

• Chemical Name: (1R,9S)-12-Phenyl-10,12,14-triaza-tricyclo[7.5.2.0^10,14]hexadec-15-ene-11,13-dione
• CAS No.: 126267-73-0
• Molecular Formula: C₁₉H₂₃N₃O₂
• Molecular Weight: 325.411
• Mol file: 126267-73-0.mol

Synonyms:(1R,9S)-12-Phenyl-10,12,14-triaza-tricyclo[7.5.2.0^10,14]hexadec-15-ene-11,13-dione

Chemical Property of (1R,9S)-12-Phenyl-10,12,14-triaza-tricyclo[7.5.2.0^10,14]hexadec-15-ene-11,13-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,9S)-12-Phenyl-10,12,14-triaza-tricyclo[7.5.2.0^10,14]hexadec-15-ene-11,13-dione

There total 1 articles about (1R,9S)-12-Phenyl-10,12,14-triaza-tricyclo[7.5.2.0^10,14]hexadec-15-ene-11,13-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

4-Phenyl-1,2,4-triazolidine-3,5-dione (4233-33-4) + cis,trans-1,3-cycloundecadiene (73683-12-2,6568-16-7) → (1R,9S)-12-Phenyl-10,12,14-triaza-tricyclo[7.5.2.010,14]hexadec-15-ene-11,13-dione (126267-73-0)

Guidance literature:

In chloroform;

DOI:10.1016/S0040-4039(01)80765-6

Reference yield: 74.0%

(1R,9S)-12-Phenyl-10,12,14-triaza-tricyclo[7.5.2.010,14]hexadec-15-ene-11,13-dione (126267-73-0) → C19H23N3O3 (126267-74-1)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4039(01)80765-6

Reference yield:

(1R,9S)-12-Phenyl-10,12,14-triaza-tricyclo[7.5.2.010,14]hexadec-15-ene-11,13-dione (126267-73-0) → 11-Oxa-13,14-diaza-tricyclo[7.3.2.010,12]tetradecane-13-carboxylic acid phenylamide (126267-75-2,126374-16-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / m-chloroperbenzoic acid / CH₂Cl₂ / Ambient temperature

2: potassium tert-butoxide / dimethylsulfoxide

With potassium tert-butylate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; dimethyl sulfoxide;

DOI:10.1016/S0040-4039(01)80765-6

upstream raw materials:

4-Phenyl-1,2,4-triazolidine-3,5-dione

cis,trans-1,3-cycloundecadiene

Downstream raw materials:

C₁₉H₂₃N₃O₃

11-Oxa-13,14-diaza-tricyclo[7.3.2.0^10,12]tetradecane-13-carboxylic acid phenylamide