1-[5-[(4-Fluorophenyl)methyl]furan-2-yl]ethanone

Base Information

Chemical Name:1-[5-[(4-Fluorophenyl)methyl]furan-2-yl]ethanone
CAS No.:280571-34-8
Molecular Formula:C₁₃H₁₁FO₂
Molecular Weight:218.228
Hs Code.:
DSSTox Substance ID:DTXSID40436026
Wikidata:Q82251204

Synonyms:280571-34-8;1-[5-[(4-fluorophenyl)methyl]furan-2-yl]ethanone;SCHEMBL3221601;DTXSID40436026;KJMDYHQKWUHDLU-UHFFFAOYSA-N;2-acetyl-5-(4-fluorobenzyl)furan;1-[5-[(4-Fluorophenyl)methyl]-2-furanyl]ethanone

Suppliers and Price of 1-[5-[(4-Fluorophenyl)methyl]furan-2-yl]ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-[5-[(4-Fluorophenyl)methyl]furan-2-yl]ethanone

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:218.07430775
Heavy Atom Count:16
Complexity:246

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1=CC=C(O1)CC2=CC=C(C=C2)F

Technology Process of 1-[5-[(4-Fluorophenyl)methyl]furan-2-yl]ethanone

There total 4 articles about 1-[5-[(4-Fluorophenyl)methyl]furan-2-yl]ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 280571-32-6
5-(4-fluorobenzyl)-furan-2-carboxylic acid

: 280571-34-8
2-acetyl-5-(4-fluorobenzyl)-furan

Guidance literature:: 5-(4-fluorobenzyl)-furan-2-carboxylic acid; With thionyl chloride; N,N-dimethyl-formamide; In toluene; at 80 ℃; for 1.5h; Ice cooling;

With methylmagnesium chloride; iron(III)-acetylacetonate; In tetrahydrofuran; at -20 ℃; for 0.666667h;

Reference yield: 53.0%

: 1192-62-7,80145-44-4
1-(2-furyl)-1-ethanone

: 352-11-4
1-chloromethyl-4-fluorobenzene

: 280571-34-8
2-acetyl-5-(4-fluorobenzyl)-furan

Guidance literature:: With palladium(II) trimethylacetate; caesium carbonate; Trimethylacetic acid; 2′-(diphenylphosphino)-N,N′-dimethyl-(1,1′-biphenyl)-2-amine; In toluene; at 110 ℃; regioselective reaction; Inert atmosphere;
DOI:10.1021/ol901689q