1,2-Dipalmitoyl-sn-glycerol

Base Information

• Chemical Name: 1,2-Dipalmitoyl-sn-glycerol
• CAS No.: 30334-71-5
• Molecular Formula: C35H68O5
• Molecular Weight: 568.922
• Hs Code.: 2915900090
• European Community (EC) Number: 250-131-4
• DSSTox Substance ID: DTXSID001036210
• Nikkaji Number: J347.938B
• Wikidata: Q27156468
• Metabolomics Workbench ID: 5795
• ChEMBL ID: CHEMBL87852
• Mol file: 30334-71-5.mol

Synonyms:1,2-Dipalmitoyl-sn-glycerol;30334-71-5;1,2-Dihexadecanoyl-sn-glycerol;(S)-1,2-Dipalmitin;DG(16:0/16:0/0:0);(S)-3-Hydroxypropane-1,2-diyl dipalmitate;[(2S)-2-hexadecanoyloxy-3-hydroxypropyl] hexadecanoate;Diacylglycerol(16:0/16:0);CHEBI:82929;(2S)-3-hydroxypropane-1,2-diyl dihexadecanoate;(S)-1-(Hydroxymethyl)ethane-1,2-diyl dipalmitate;DAG(16:0/16:0);Hexadecanoic acid, (1S)-1-(hydroxymethyl)-1,2-ethanediyl ester;DG(16:0/16:0);C35H68O5;Hexadecanoic acid, 1-(hydroxymethyl)-1,2-ethanediyl ester, (S)-;(S)-Glycerol 1,2-dipalmitate;C35-H68-O5;D-,-Dipalmitin;761-35-3;CMC_6810;L-1,2-Dipalmitin;sn-1,2-Dipalmitin;(?)-1,2-Dipalmitin;1,2-Dipalmitin-sn-glycerol;CHEMBL87852;SCHEMBL594854;(S)-(-)-1,2-Dipalmitin;1,2-Di-O-palmitoyl-sn-glycerol;DTXSID001036210;Palmitin, L-1,2-di- (6CI);CMC_7218;CMC_8101;CMC_10485;CMC_11730;CMC_12683;LMGL02010009;MFCD00067471;Palmitin, 1,2-di-, L- (8CI);CS-W011452;HY-W010736;1,2-Dipalmitoyl-sn-glycerol, >=99%;AS-75956;BP-29827;(S)-3-Hydroxypropane-1,2-diyldipalmitate;D97630;Q27156468;Hexadecanoic acid, (1S)-1-(hydroxymethyl)-1,2-ethanediyl ester (9CI);Hexadecanoic acid,1,1'-[(1S)-1-(hydroxymethyl)-1,2-ethanediyl]ester;hexadecanoic acid, (1S)-2-hydroxy-1-[[(1-oxohexadecyl)oxy]methyl]ethyl ester;8ND

Chemical Property of 1,2-Dipalmitoyl-sn-glycerol

Chemical Property:

• Vapor Pressure: 5.19E-18mmHg at 25°C
• Melting Point: 66-69 °C
• Refractive Index: 1.465
• Boiling Point: 620.8°Cat760mmHg
• PKA: 13.69±0.10(Predicted)
• Flash Point: 174.7°C
• PSA: 72.83000
• Density: 0.93g/cm³
• LogP: 10.39630
• Storage Temp.: −20°C
• XLogP3: 14
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 34
• Exact Mass: 568.50667527
• Heavy Atom Count: 40
• Complexity: 536

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,2-Dipalmitoyl-sn-glycerol 99+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCCCCCCCCC
• Isomeric SMILES: CCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCCCCCCCCCC
• General Description: **1,2-DIPALMITOYL-SN-GLYCEROL** is an asymmetric 1,2-diacyl-sn-glycerol derivative that exhibits diverse helical conformational behaviors in solution, including rapid equilibrium among *gt*(+), *gg*(?), and *tg* conformers. Its conformational properties are influenced by solvent conditions and follow an empirical rule relating helical disparity (%) to the population of the *gt*(+) conformer, as described by the equation: *helical disparity (%)* = 1.3[*gt*(+) ? 38]. This rule holds across various 1,2-diacyl-sn-glycerols, providing a framework for understanding their dynamic structural behavior in solution.

Technology Process of 1,2-Dipalmitoyl-sn-glycerol

There total 19 articles about 1,2-Dipalmitoyl-sn-glycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,2-di-O-hexacecanoyl-3-O-benzyl-sn-glycerol (30403-51-1) → 1,2-dipalmitoyl-sn-glycerol (30334-71-5)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; acetic acid; In ethanol; at 20 ℃; for 12h;

DOI:10.1021/acs.orglett.0c00487

Reference yield: 98.0%

(+)-3-O-(4-methoxybenzyl)-1,2-di-O-hexadecanoyl-sn-glycerol (183430-01-5) → 1,2-dipalmitoyl-sn-glycerol (30334-71-5)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; acetic acid; for 3h;

DOI:10.1021/jo961226g

Reference yield: 96.0%

Hexadecanoic acid (S)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-1-hexadecanoyloxymethyl-ethyl ester → 1,2-dipalmitoyl-sn-glycerol (30334-71-5)

Guidance literature:

In methanol; tetrachloromethane; at 25 - 40 ℃; for 1h; ultrasonic;

DOI:10.1080/00397919708005904

upstream raw materials:

1,2-di-O-hexacecanoyl-3-O-benzyl-sn-glycerol

Hexadecanoic acid (S)-2-(3,4-dimethoxy-benzyloxy)-1-hexadecanoyloxymethyl-ethyl ester

(+)-3-O-(4-methoxybenzyl)-1,2-di-O-hexadecanoyl-sn-glycerol

Hexadecanoic acid (R)-2-(9H-fluoren-9-ylmethoxycarbonyloxy)-1-hexadecanoyloxymethyl-ethyl ester

Downstream raw materials:

Hexadecanoic acid (R)-2-(chloro-phenoxy-phosphoryloxy)-1-hexadecanoyloxymethyl-ethyl ester

Hexadecanoic acid (R)-1-hexadecanoyloxymethyl-2-(hydroxy-phenoxy-phosphoryloxy)-ethyl ester

Hexadecanoic acid (R)-2-[benzyloxy-((1R,2R,3S,4R)-2,3,4-tris-benzyloxy-cyclohexyloxy)-phosphanyloxy]-1-hexadecanoyloxymethyl-ethyl ester

1,2-dipalmitoyl-sn-glycerol-3-O-succinic acid monoester