N-(2,2-dimethyl-1-(4-methyl-5-morpholinooxazol-2-yl)propyl)-4-(trifluoromethyl)benzenamine

Base Information

• Chemical Name: N-(2,2-dimethyl-1-(4-methyl-5-morpholinooxazol-2-yl)propyl)-4-(trifluoromethyl)benzenamine
• CAS No.: 1192278-13-9
• Molecular Formula: C₂₀H₂₆F₃N₃O₂
• Molecular Weight: 397.441

Synonyms:N-(2,2-dimethyl-1-(4-methyl-5-morpholinooxazol-2-yl)propyl)-4-(trifluoromethyl)benzenamine

Chemical Property of N-(2,2-dimethyl-1-(4-methyl-5-morpholinooxazol-2-yl)propyl)-4-(trifluoromethyl)benzenamine

Chemical Property:

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Technology Process of N-(2,2-dimethyl-1-(4-methyl-5-morpholinooxazol-2-yl)propyl)-4-(trifluoromethyl)benzenamine

There total 1 articles about N-(2,2-dimethyl-1-(4-methyl-5-morpholinooxazol-2-yl)propyl)-4-(trifluoromethyl)benzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-isocyano-1-morpholinopropan-1-one + C12H14F3N (1236962-43-8) → N-(2,2-dimethyl-1-(4-methyl-5-morpholinooxazol-2-yl)propyl)-4-(trifluoromethyl)benzenamine (1192278-13-9) + N-(2,2-dimethyl-1-(4-methyl-5-morpholinooxazol-2-yl)propyl)-4-(trifluoromethyl)benzenamine

Guidance literature:

With R-TRIP; In toluene; at -20 - 20 ℃; optical yield given as %ee; enantioselective reaction;

DOI:10.1002/anie.200902385

upstream raw materials:

C₁₂H₁₄F₃N

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