1,4-dideoxy-1,4-{(S)-[4-deoxy-2-O-(o-methylbenzyl)-D-erythritol-4-yl]-episulfoniumylidene}-D-arabinitol chloride

Base Information

• Chemical Name: 1,4-dideoxy-1,4-{(S)-[4-deoxy-2-O-(o-methylbenzyl)-D-erythritol-4-yl]-episulfoniumylidene}-D-arabinitol chloride
• CAS No.: 1392479-79-6
• Molecular Formula: C₁₇H₂₇O₆S*Cl
• Molecular Weight: 394.917
• Mol file: 1392479-79-6.mol

Synonyms:1,4-dideoxy-1,4-{(S)-[4-deoxy-2-O-(o-methylbenzyl)-D-erythritol-4-yl]-episulfoniumylidene}-D-arabinitol chloride

Chemical Property of 1,4-dideoxy-1,4-{(S)-[4-deoxy-2-O-(o-methylbenzyl)-D-erythritol-4-yl]-episulfoniumylidene}-D-arabinitol chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-dideoxy-1,4-{(S)-[4-deoxy-2-O-(o-methylbenzyl)-D-erythritol-4-yl]-episulfoniumylidene}-D-arabinitol chloride

There total 8 articles about 1,4-dideoxy-1,4-{(S)-[4-deoxy-2-O-(o-methylbenzyl)-D-erythritol-4-yl]-episulfoniumylidene}-D-arabinitol chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

1,4-dideoxy-1,4-{(R)-[4-deoxy-1-O-(p-methoxybenzyl)-2-O-(o-methylbenzyl)-D-erythritol-4-yl]episulfoniumylidene}-2,3,5-tri-O-(p-methoxybenzyl)-D-arabinitol tetrafluoroborate → 1,4-dideoxy-1,4-{(S)-[4-deoxy-2-O-(o-methylbenzyl)-D-erythritol-4-yl]-episulfoniumylidene}-D-arabinitol chloride (1392479-79-6)

Guidance literature:

1,4-dideoxy-1,4-{(R)-[4-deoxy-1-O-(p-methoxybenzyl)-2-O-(o-methylbenzyl)-D-erythritol-4-yl]episulfoniumylidene}-2,3,5-tri-O-(p-methoxybenzyl)-D-arabinitol tetrafluoroborate; With trifluoroacetic acid; In chloroform; water; at 20 ℃; for 5h;

IRA-400J (Cl^- form); In methanol; for 12h; diastereoselective reaction;

DOI:10.1021/acs.joc.7b02566

Reference yield:

BF4(1-)*C17H27O6S(1+) → 1,4-dideoxy-1,4-{(S)-[4-deoxy-2-O-(o-methylbenzyl)-D-erythritol-4-yl]-episulfoniumylidene}-D-arabinitol chloride (1392479-79-6)

Guidance literature:

With RA-400J (Cl^- form); In methanol; at 20 ℃;

DOI:10.1039/c2cc34144a

Reference yield:

2,3,5-tri-O-(p-methoxybenzyl)-1,4-dideoxy-1,4-epithio-D-arabinitol → 1,4-dideoxy-1,4-{(S)-[4-deoxy-2-O-(o-methylbenzyl)-D-erythritol-4-yl]-episulfoniumylidene}-D-arabinitol chloride (1392479-79-6)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrafluoroboric acid alkyl ether complex / dichloromethane / -60 °C

2: trifluoroacetic acid / chloroform; water / 20 °C

3: RA-400J (Cl^- form) / methanol / 20 °C

With trifluoroacetic acid; In methanol; dichloromethane; chloroform; water;

DOI:10.1039/c2cc34144a