(3aR)-2-(2,6-difluorophenyl)-5,10-diphenyl-3a,4,11,11a-tetrahydro-1H-4,11-ethenonaphtho[2,3-f]isoindole-1,3(2H)-dione

Base Information

• Chemical Name: (3aR)-2-(2,6-difluorophenyl)-5,10-diphenyl-3a,4,11,11a-tetrahydro-1H-4,11-ethenonaphtho[2,3-f]isoindole-1,3(2H)-dione
• CAS No.: 1617526-43-8
• Molecular Formula: C₃₆H₂₃F₂NO₂
• Molecular Weight: 539.581

Synonyms:(3aR)-2-(2,6-difluorophenyl)-5,10-diphenyl-3a,4,11,11a-tetrahydro-1H-4,11-ethenonaphtho[2,3-f]isoindole-1,3(2H)-dione

Chemical Property of (3aR)-2-(2,6-difluorophenyl)-5,10-diphenyl-3a,4,11,11a-tetrahydro-1H-4,11-ethenonaphtho[2,3-f]isoindole-1,3(2H)-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3aR)-2-(2,6-difluorophenyl)-5,10-diphenyl-3a,4,11,11a-tetrahydro-1H-4,11-ethenonaphtho[2,3-f]isoindole-1,3(2H)-dione

There total 3 articles about (3aR)-2-(2,6-difluorophenyl)-5,10-diphenyl-3a,4,11,11a-tetrahydro-1H-4,11-ethenonaphtho[2,3-f]isoindole-1,3(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-(2,6-difluorophenyl)pyrrole-2,5-dione + 9,10-diphenylanthracene (1499-10-1) → (3aR)-2-(2,6-difluorophenyl)-5,10-diphenyl-3a,4,11,11a-tetrahydro-1H-4,11-ethenonaphtho[2,3-f]isoindole-1,3(2H)-dione (1617526-43-8)

Guidance literature:

With aluminum (III) chloride; In chloroform; at 20 ℃; for 1h; Temperature; Solvent; stereoselective reaction;

DOI:10.1021/acs.orglett.5b02487

Reference yield:

2,6-difluoroaniline (5509-65-9) → (3aR)-2-(2,6-difluorophenyl)-5,10-diphenyl-3a,4,11,11a-tetrahydro-1H-4,11-ethenonaphtho[2,3-f]isoindole-1,3(2H)-dione (1617526-43-8)

Guidance literature:

Multi-step reaction with 3 steps

1: diethyl ether

2: acetic anhydride; sodium acetate / 90 °C

3: 120 h / 140 °C

With sodium acetate; acetic anhydride; In diethyl ether; 3: |Diels-Alder Cycloaddition;

DOI:10.1039/c4ob01052c

Reference yield:

C10H7F2NO3 (658072-12-9) → (3aR)-2-(2,6-difluorophenyl)-5,10-diphenyl-3a,4,11,11a-tetrahydro-1H-4,11-ethenonaphtho[2,3-f]isoindole-1,3(2H)-dione (1617526-43-8)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic anhydride; sodium acetate / 90 °C

2: 120 h / 140 °C

With sodium acetate; acetic anhydride; 2: |Diels-Alder Cycloaddition;

DOI:10.1039/c4ob01052c

upstream raw materials:

9,10-diphenylanthracene

2,6-difluoroaniline

C₁₀H₇F₂NO₃

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1617526-43-8 (3aR)-2-(2,6-difluorophenyl)-5,10-diphenyl-3a,4,11,11a-tetrahydro-1H-4,11-ethenonaphtho[2,3-f]isoindole-1,3(2H)-dione

Send

Send

Metric Ton KG G Pound L ML

Send

Send