Technology Process of tert-butyl 2-diazo-2-(4-methylphenyl)acetate
There total 5 articles about tert-butyl 2-diazo-2-(4-methylphenyl)acetate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
o-nitrobenzenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
acetonitrile;
at 0 - 20 ℃;
Schlenk technique;
Inert atmosphere;
Darkness;
DOI:10.1002/chem.202000081
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sulfuric acid; magnesium sulfate / dichloromethane / 40 °C
2: 4-acetamidobenzenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile
With
sulfuric acid; 4-acetamidobenzenesulfonyl azide; magnesium sulfate; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
dichloromethane; acetonitrile;
DOI:10.1021/acs.joc.0c01590
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tri-tert-butyl phosphine; lithium hexamethyldisilazane; bis(dibenzylideneacetone)-palladium(0) / toluene / 0 - 20 °C / Inert atmosphere
2: 4-acetamidobenzenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 0 - 20 °C / Inert atmosphere
With
tri-tert-butyl phosphine; 4-acetamidobenzenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium hexamethyldisilazane; bis(dibenzylideneacetone)-palladium(0);
In
toluene; acetonitrile;
DOI:10.1021/ja209270e
