7alpha-Methyl-4-pregnene-3,20-dione

Base Information

• Chemical Name: 7alpha-Methyl-4-pregnene-3,20-dione
• CAS No.: 2640-71-3
• Molecular Formula: C₂₂H₃₂O₂
• Molecular Weight: 328.495
• ChEMBL ID: CHEMBL3273981
• Nikkaji Number: J128.011B
• Wikidata: Q27148937
• Mol file: 2640-71-3.mol

Synonyms:7alpha-Methyl-4-pregnene-3,20-dione;CHEBI:79801;(7R,8S,9S,10R,13S,14S,17S)-17-acetyl-7,10,13-trimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one;7.alpha.-Methylprogesterone;7alpha-Methylprogesterone;Progesterone, 7.alpha.-methyl-;SK 22942;Pregn-4-ene-3,20-dione, 7.alpha.-methyl-;Pregn-4-ene-3,20-dione, 7-methyl-, (7.alpha.)-;CHEMBL3273981;ZJTSNYHPKIGSEQ-WYVJSDDNSA-N;7-Methylpregn-4-ene-3,20-dione #;Q27148937

Chemical Property of 7alpha-Methyl-4-pregnene-3,20-dione

Chemical Property:

• Vapor Pressure: 2.03E-08mmHg at 25°C
• Boiling Point: 453.7°Cat760mmHg
• Flash Point: 169°C
• PSA: 34.14000
• Density: 1.07g/cm³
• LogP: 4.96950
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 328.240230259
• Heavy Atom Count: 24
• Complexity: 618

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CC2=CC(=O)CCC2(C3C1C4CCC(C4(CC3)C)C(=O)C)C
• Isomeric SMILES: C[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@@H]([C@]4(CC3)C)C(=O)C)C

Technology Process of 7alpha-Methyl-4-pregnene-3,20-dione

There total 2 articles about 7alpha-Methyl-4-pregnene-3,20-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

20αF-hydroxy-pregn-4-en-3-one (145-14-2,145-15-3,4243-72-5,4707-79-3,4877-83-2,15114-79-1) → 7α-methyl-4-pregnene-3,20-dione (2640-71-3)

Guidance literature:

Reaktion ueber mehrere Stufen;

DOI:10.1021/ja01524a063

Reference yield:

→ (7R,10R,13S,17S)-17-Acetyl-7,10,13-trimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one (1946-15-2,2640-71-3,4077-01-4,95403-61-5)

Guidance literature:

upstream raw materials:

20α_F-hydroxy-pregn-4-en-3-one