methyl N-(tert-butoxycarbonyl)-4-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6, 7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]piperidin-1-yl}isovalinate

Base Information

Chemical Name:methyl N-(tert-butoxycarbonyl)-4-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6, 7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]piperidin-1-yl}isovalinate
CAS No.:1192344-44-7
Molecular Formula:C₃₈H₅₆N₈O₇
Molecular Weight:736.912
Hs Code.:

methyl N-(tert-butoxycarbonyl)-4-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6, 7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]piperidin-1-yl}isovalinate

Synonyms:methyl N-(tert-butoxycarbonyl)-4-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6, 7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]piperidin-1-yl}isovalinate

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Chemical Property of methyl N-(tert-butoxycarbonyl)-4-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6, 7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]piperidin-1-yl}isovalinate

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Technology Process of methyl N-(tert-butoxycarbonyl)-4-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6, 7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]piperidin-1-yl}isovalinate

There total 1 articles about methyl N-(tert-butoxycarbonyl)-4-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6, 7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]piperidin-1-yl}isovalinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1021853-33-7
4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-piperidin-4-ylbenzamide

: 308817-62-1
methyl 4-oxoisovalinate

: 1192344-44-7
methyl N-(tert-butoxycarbonyl)-4-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6, 7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]piperidin-1-yl}isovalinate

Guidance literature:: 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-piperidin-4-ylbenzamide; methyl 4-oxoisovalinate; In 1,1-dichloroethane; at 20 ℃; for 0.25h;

With sodium tris(acetoxy)borohydride; In 1,1-dichloroethane; at 20 ℃;

With sodium hydrogencarbonate; In dichloromethane; 1,2-dichloro-ethane;

Reference yield: 12.0%

: 1192344-44-7
methyl N-(tert-butoxycarbonyl)-4-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6, 7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]piperidin-1-yl}isovalinate

: 1192344-45-8
methyl 4-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]piperidin-1-yl}isovalinate

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 1192344-44-7
methyl N-(tert-butoxycarbonyl)-4-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6, 7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]piperidin-1-yl}isovalinate

: C₃₇H₅₄N₈O₇

Guidance literature:: methyl N-(tert-butoxycarbonyl)-4-{4-[(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6, 7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzoyl)amino]piperidin-1-yl}isovalinate; With water; lithium hydroxide; In tetrahydrofuran; at 40 ℃;

With hydrogenchloride; In water; pH=1 - 2;