Modopar

Base Information

• Chemical Name: Modopar
• CAS No.: 37270-69-2
• Deprecated CAS: 61949-25-5
• Molecular Formula: C19H26N4O9
• Molecular Weight: 454.433
• DSSTox Substance ID: DTXSID80958414
• Mol file: 37270-69-2.mol

Synonyms:benserazide - levodopa;benserazide, levodopa drug combination;madopa;madopar;modopar;Ro 8-0576;Ro 8-0576-12;Ro 8-0576-7

Chemical Property of Modopar

Chemical Property:

• Boiling Point: 574.2°Cat760mmHg
• Flash Point: 301°C
• PSA: 255.34000
• Density: g/cm³
• LogP: 0.92780
• Hydrogen Bond Donor Count: 11
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 8
• Exact Mass: 454.16997842
• Heavy Atom Count: 32
• Complexity: 487

Purity/Quality:

MADOPAR 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1CC(C(=O)O)N)O)O.C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O
• Isomeric SMILES: C1=CC(=C(C=C1C[C@@H](C(=O)O)N)O)O.C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O
• Recent EU Clinical Trials: R?le de la dopamine dans le comportement d’aversion à la perte : étude chez le patient parkinsonien
• Clinical Use: #N/A
• Drug interactions: Potentially hazardous interactions with other drugs Anaesthetics: risk of arrhythmias with volatile liquid anaesthetics such as halothane. Antidepressants: hypertensive crisis with MAOIs and linezolid (including moclobemide) - avoid for at least 2 weeks after stopping MAOI. Bupropion: increased risk of side effects of levodopa Ferrous sulphate: reduces AUC of levodopa by 30-50%, clinically significant in some but not all patients.