6-(((benzyloxy)carbonyl)amino)-6-methyl-1-phenylheptan-3-yl sulfamate

Base Information

• Chemical Name: 6-(((benzyloxy)carbonyl)amino)-6-methyl-1-phenylheptan-3-yl sulfamate
• CAS No.: 1609949-22-5
• Molecular Formula: C₂₂H₃₀N₂O₅S
• Molecular Weight: 434.557
• Mol file: 1609949-22-5.mol

Synonyms:6-(((benzyloxy)carbonyl)amino)-6-methyl-1-phenylheptan-3-yl sulfamate

Chemical Property of 6-(((benzyloxy)carbonyl)amino)-6-methyl-1-phenylheptan-3-yl sulfamate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 6-(((benzyloxy)carbonyl)amino)-6-methyl-1-phenylheptan-3-yl sulfamate

There total 1 articles about 6-(((benzyloxy)carbonyl)amino)-6-methyl-1-phenylheptan-3-yl sulfamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

C22H29NO3 (1609948-98-2) → 6-(((benzyloxy)carbonyl)amino)-6-methyl-1-phenylheptan-3-yl sulfamate (1609949-22-5)

Guidance literature:

With sulphamoyl chloride; In N,N-dimethyl acetamide; acetonitrile; at 20 ℃;

DOI:10.1055/s-0033-1340159

Reference yield: 88.0%

6-(((benzyloxy)carbonyl)amino)-6-methyl-1-phenylheptan-3-yl sulfamate (1609949-22-5) → benzyl (4-((4SR,6SR)-2,2-dioxido-4-phenyl-1,2,3-oxathiazinan-6-yl)-2-methylbutan-2-yl)carbamate

Guidance literature:

With dirhodium tetraacetate; [bis(acetoxy)iodo]benzene; magnesium oxide; In dichloromethane; at 20 ℃; stereoselective reaction;

DOI:10.1055/s-0033-1340159

Reference yield:

6-(((benzyloxy)carbonyl)amino)-6-methyl-1-phenylheptan-3-yl sulfamate (1609949-22-5) → tert-butyl (4SR,6SR)-6-(3-(((benzyloxy)carbonyl)amino)-3-methylbutyl)-4-phenyl-1,2,3-oxathiazinane-3-carboxylate 2,2-dioxide

Guidance literature:

Multi-step reaction with 2 steps

1: magnesium oxide; [bis(acetoxy)iodo]benzene; dirhodium tetraacetate / dichloromethane / 20 °C

2: dmap; triethylamine / dichloromethane / 20 °C

With dmap; dirhodium tetraacetate; [bis(acetoxy)iodo]benzene; magnesium oxide; triethylamine; In dichloromethane;

DOI:10.1055/s-0033-1340159

upstream raw materials:

C₂₂H₂₉NO₃