Technology Process of 2-methyl-3-(1-naphthyl)iodobenzene
There total 4 articles about 2-methyl-3-(1-naphthyl)iodobenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid; potassium iodide; sodium nitrite;
In
water; acetonitrile;
at 0 - 20 ℃;
for 12h;
Inert atmosphere;
DOI:10.1039/c0jm02877k
- Guidance literature:
-
Multi-step reaction with 3 steps
1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / 1,2-dimethoxyethane; water / Inert atmosphere; Reflux
2: palladium 10% on activated carbon; hydrogen / ethanol; ethyl acetate / 5 h / 1551.49 Torr / Inert atmosphere
3: toluene-4-sulfonic acid; potassium iodide; sodium nitrite / water; acetonitrile / 12 h / 0 - 20 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); palladium 10% on activated carbon; hydrogen; potassium carbonate; toluene-4-sulfonic acid; potassium iodide; sodium nitrite;
In
1,2-dimethoxyethane; ethanol; water; ethyl acetate; acetonitrile;
1: Suzuki coupling / 3: Sandmeyer reaction;
DOI:10.1039/c0jm02877k
- Guidance literature:
-
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen / ethanol; ethyl acetate / 5 h / 1551.49 Torr / Inert atmosphere
2: toluene-4-sulfonic acid; potassium iodide; sodium nitrite / water; acetonitrile / 12 h / 0 - 20 °C / Inert atmosphere
With
palladium 10% on activated carbon; hydrogen; toluene-4-sulfonic acid; potassium iodide; sodium nitrite;
In
ethanol; water; ethyl acetate; acetonitrile;
2: Sandmeyer reaction;
DOI:10.1039/c0jm02877k
