(R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine

Base Information

Chemical Name:(R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine
CAS No.:1429560-52-0
Molecular Formula:C₁₆H₂₄N₂O₃
Molecular Weight:292.378
Hs Code.:

Synonyms:(R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine

Suppliers and Price of (R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of (R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine

Chemical Property:

Purity/Quality:: 98% ,99% , ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine

There total 3 articles about (R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 1383146-20-0
(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one

: 368-39-8
triethyloxonium fluoroborate

: 1429560-52-0
(R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine

Guidance literature:: With sodium carbonate; In dichloromethane; at 15 - 20 ℃; for 0.75h; Inert atmosphere;
DOI:10.1021/jm5017413

Reference yield:

: 613-45-6
2,4-Dimethoxybenzaldehyde

: 1429560-52-0
(R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tris(acetoxy)borohydride; acetic acid / acetonitrile / 20 °C / Inert atmosphere

2: sodium carbonate / dichloromethane / 1 h / 20 °C / Inert atmosphere

With sodium tris(acetoxy)borohydride; sodium carbonate; acetic acid; In dichloromethane; acetonitrile;

Reference yield:

: 922178-61-8
?(R)-3-methylpiperazin-2-one

: 1429560-52-0
(R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tris(acetoxy)borohydride; acetic acid / acetonitrile / 20 °C / Inert atmosphere

2: sodium carbonate / dichloromethane / 1 h / 20 °C / Inert atmosphere

With sodium tris(acetoxy)borohydride; sodium carbonate; acetic acid; In dichloromethane; acetonitrile;