Technology Process of (3-(cyclopropylmethylthio))phenylmethanamine
There total 3 articles about (3-(cyclopropylmethylthio))phenylmethanamine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C11H13N3S;
With
hydrogen;
palladium 10% on activated carbon;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
With
water; sodium hydroxide;
In
tetrahydrofuran;
at 0 ℃;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 90 °C
2.1: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 1 h / 20 °C
3.1: hydrogen / palladium 10% on activated carbon / tetrahydrofuran / 1 h / 20 °C
3.2: 0 °C
With
diphenyl phosphoryl azide; hydrogen; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene;
palladium 10% on activated carbon;
In
tetrahydrofuran; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 1 h / 20 °C
2.1: hydrogen / palladium 10% on activated carbon / tetrahydrofuran / 1 h / 20 °C
2.2: 0 °C
With
diphenyl phosphoryl azide; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene;
palladium 10% on activated carbon;
In
tetrahydrofuran;
