6-nitro-4-(phenylsulfonyl)benzo[d]isoxazole-3-carboxaldehyde O-methyloxime

Base Information

• Chemical Name: 6-nitro-4-(phenylsulfonyl)benzo[d]isoxazole-3-carboxaldehyde O-methyloxime
• CAS No.: 663622-97-7
• Molecular Formula: C₁₅H₁₁N₃O₆S
• Molecular Weight: 361.335
• Mol file: 663622-97-7.mol

Synonyms:6-nitro-4-(phenylsulfonyl)benzo[d]isoxazole-3-carboxaldehyde O-methyloxime

Chemical Property of 6-nitro-4-(phenylsulfonyl)benzo[d]isoxazole-3-carboxaldehyde O-methyloxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-nitro-4-(phenylsulfonyl)benzo[d]isoxazole-3-carboxaldehyde O-methyloxime

There total 1 articles about 6-nitro-4-(phenylsulfonyl)benzo[d]isoxazole-3-carboxaldehyde O-methyloxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

6-nitro-4-(phenylthio)benzo[d]isoxazole-3-carboxaldehyde O-methyloxime (369390-06-7) → 6-nitro-4-(phenylsulfonyl)benzo[d]isoxazole-3-carboxaldehyde O-methyloxime (663622-97-7)

Guidance literature:

With dihydrogen peroxide; trifluoroacetic acid; In water; at 20 ℃; for 1h;

DOI:10.1023/A:1026012922607

Reference yield: 64.0%

thiophenol (108-98-5) + 6-nitro-4-(phenylsulfonyl)benzo[d]isoxazole-3-carboxaldehyde O-methyloxime (663622-97-7) → 6-nitro-4-(phenylthio)benzo[d]isoxazole-3-carboxaldehyde O-methyloxime (369390-06-7)

Guidance literature:

With potassium carbonate; In 1-methyl-pyrrolidin-2-one; at 20 ℃;

DOI:10.1023/A:1026012922607

Reference yield:

6-nitro-4-(phenylsulfonyl)benzo[d]isoxazole-3-carboxaldehyde O-methyloxime (663622-97-7) → 4,6-bis(phenylthio)benzo[d]isoxazole-3-carboxaldehyde O-methyloxime

Guidance literature:

Multi-step reaction with 2 steps

1: 64 percent / K₂CO₃ / 1-methyl-pyrrolidin-2-one / 20 °C

2: 63 percent / K₂CO₃ / 1-methyl-pyrrolidin-2-one / 10 h / 100 °C

With potassium carbonate; In 1-methyl-pyrrolidin-2-one;

DOI:10.1023/A:1026012922607

upstream raw materials:

6-nitro-4-(phenylthio)benzo[d]isoxazole-3-carboxaldehyde O-methyloxime

Downstream raw materials:

6-nitro-4-(phenylthio)benzo[d]isoxazole-3-carboxaldehyde O-methyloxime