N^α-(tert-Butyloxycarbonyl)-N^ε-10-methylpteroyl)-L-γ-glutamyl>-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysine Benzyl (O^α-glu) Ester

Base Information

• Chemical Name: N^α-(tert-Butyloxycarbonyl)-N^ε-10-methylpteroyl)-L-γ-glutamyl>-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysine Benzyl (O^α-glu) Ester
• CAS No.: 89106-09-2
• Molecular Formula: C₆₆H₈₄N₁₄O₁₄
• Molecular Weight: 1297.48

Synonyms:N^α-(tert-Butyloxycarbonyl)-N^ε-10-methylpteroyl)-L-γ-glutamyl>-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysine Benzyl (O^α-glu) Ester

Chemical Property of N^α-(tert-Butyloxycarbonyl)-N^ε-10-methylpteroyl)-L-γ-glutamyl>-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysine Benzyl (O^α-glu) Ester

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Technology Process of N^α-(tert-Butyloxycarbonyl)-N^ε-10-methylpteroyl)-L-γ-glutamyl>-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysine Benzyl (O^α-glu) Ester

There total 1 articles about N^α-(tert-Butyloxycarbonyl)-N^ε-10-methylpteroyl)-L-γ-glutamyl>-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysine Benzyl (O^α-glu) Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

Nα-(tert-Butyloxycarbonyl)-Nε-10-methylpteroyl)-L-γ-glutamyl>-L-lysyl-Nε-(benzyloxycarbonyl)-L-lysyl-Nε-(benzyloxycarbonyl)-L-lysine Benzyl (Oα-glu) 2-(Trimethylsilyl)ethyl (Olys) Ester (89106-02-5) → Nα-(tert-Butyloxycarbonyl)-Nε-10-methylpteroyl)-L-γ-glutamyl>-L-lysyl-Nε-(benzyloxycarbonyl)-L-lysyl-Nε-(benzyloxycarbonyl)-L-lysine Benzyl (Oα-glu) Ester (89106-09-2)

Guidance literature:

With KF*F^(1-); tetrabutyl-ammonium chloride; In N,N-dimethyl-formamide; at 55 ℃; for 36h;

DOI:10.1021/jo00181a043

upstream raw materials:

N^α-(tert-Butyloxycarbonyl)-N^ε-10-methylpteroyl)-L-γ-glutamyl>-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysine Benzyl (O^α-glu) 2-(Trimethylsilyl)ethyl (O^lys) Ester

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