phosphoric acid, sodium salt

Base Information

• Chemical Name: phosphoric acid, sodium salt
• CAS No.: 7632-05-5
• Molecular Formula: H3O4P.xNa
• Molecular Weight: 163.94100
• Hs Code.: 2835291000
• Mol file: 7632-05-5.mol

Synonyms:Phosphoricacid, sodium salt (8CI,9CI);Armite;Buromin;Casen-Fleet;E 339;FleetEZ-Prep;Fleet Phospho-Soda;Fosfosoda;Hy-Phos;INKP 100;Instant Calgon;Phospho-soda EZ-Prep;Phosphosoda;Sodium orthophosphate;Turrixin ST;

Chemical Property of phosphoric acid, sodium salt

Chemical Property:

• Boiling Point: 158oC at 760 mmHg
• PSA: 96.06000
• LogP: 0.38600

Purity/Quality:

99% ^*data from raw suppliers

PHOSPHORIC ACID SODIUM SALT 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R34:
• Hazard Codes: C:Corrosive
• Statements: R34:
• Safety Statements: S26:; S36/37/39:; S45:

MSDS Files:

SDS file from LookChem

Useful:

Refernces

Design of β-amyloid aggregation inhibitors from a predicted structural motif

10.1021/jm201332p

The study focuses on the design of inhibitors for β-amyloid (Aβ) aggregation, a key process in Alzheimer's disease (AD). Researchers developed a substituted peptide, [Nle35, D-Pro37]Aβ42, using molecular dynamics simulations to stabilize Aβ structures suitable for NMR analysis. This peptide was found to stabilize Aβ trimers, prevent mature fibril and β-sheet formation, and reduce aggregation when mixed with wild-type Aβ42. Furthermore, a small molecule lead compound was identified through ligand-based drug design, showing similar inhibitory effects to the peptide. The study demonstrates the potential of using molecular dynamics simulation to guide experiments aimed at understanding AD and developing therapeutics.