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(5bR)-5,5bα,6,6aβ,10,11,16,16b,16cα,17,19,20-Dodecahydro-16bβ-methylbisindolo[2',3':3,4]pyrido[2,1-a:2',1'-g][2,7]naphthyridine-7-carboxylic acid methyl ester

Base Information
  • Chemical Name:(5bR)-5,5bα,6,6aβ,10,11,16,16b,16cα,17,19,20-Dodecahydro-16bβ-methylbisindolo[2',3':3,4]pyrido[2,1-a:2',1'-g][2,7]naphthyridine-7-carboxylic acid methyl ester
  • CAS No.:27802-03-5
  • Molecular Formula:C31H32N4O2
  • Molecular Weight:492.621
  • Hs Code.:
  • Mol file:27802-03-5.mol
(5bR)-5,5bα,6,6aβ,10,11,16,16b,16cα,17,19,20-Dodecahydro-16bβ-methylbisindolo[2',3':3,4]pyrido[2,1-a:2',1'-g][2,7]naphthyridine-7-carboxylic acid methyl ester

Synonyms:Bisindolo[2',3':3,4]pyrido[2,1-a:2',1'-g][2,7]naphthyridine-7-carboxylicacid, 5,5b,6,6a,10,11,16,16b,16c,17,19,20-dodecahydro-16b-methyl-, methylester, (5bR,6aS,16bS,16cR)- (9CI); Roxburghine; Roxburghine D (8CI);Bisindolo[2',3':3,4]pyrido[2,1-a:2',1'-g][2,7]naphthyridine-7-carboxylic acid,5,5b,6,6a,10,11,16,16b,16c,17,19,20-dodecahydro-16b-methyl-, methyl ester,[5bR-(5ba,6ab,16bb,16ca)]-; Roxburghin; Roxburghin D;[5bR-(5ba,6ab,16bb,16ca)]-Methyl5,5b,6,6a,10,11,16,16b,16c,17,19,20-dodecahydro-16b-methylbisindolo[2',3':3,4]pyrido[2,1-a:2',1'-g][2,7]naphthyridine-7-carboxylate

Suppliers and Price of (5bR)-5,5bα,6,6aβ,10,11,16,16b,16cα,17,19,20-Dodecahydro-16bβ-methylbisindolo[2',3':3,4]pyrido[2,1-a:2',1'-g][2,7]naphthyridine-7-carboxylic acid methyl ester
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
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Chemical Property of (5bR)-5,5bα,6,6aβ,10,11,16,16b,16cα,17,19,20-Dodecahydro-16bβ-methylbisindolo[2',3':3,4]pyrido[2,1-a:2',1'-g][2,7]naphthyridine-7-carboxylic acid methyl ester
Chemical Property:
  • Melting Point:197-200°C 
  • PSA:64.36000 
  • LogP:4.90430 
Purity/Quality:

99% *data from raw suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Description This alkaloid also occurs in the leaves of Uncaria gambier and forms colourless crystals from MeOH. It is, unlike the remaining alkaloids, dextrorotatory with [α]20D + 160° (MeOH) but the ultraviolet spectrum in EtOH is almost identical with those of the preceding bases, having absorption maxima at 226 and 292 ITIJ1 with a shoulder at 287 mfl. On catalytic hydrogenation it gives the dihydro derivative, m.p. 225-230°C.
Technology Process of (5bR)-5,5bα,6,6aβ,10,11,16,16b,16cα,17,19,20-Dodecahydro-16bβ-methylbisindolo[2',3':3,4]pyrido[2,1-a:2',1'-g][2,7]naphthyridine-7-carboxylic acid methyl ester

There total 1 articles about (5bR)-5,5bα,6,6aβ,10,11,16,16b,16cα,17,19,20-Dodecahydro-16bβ-methylbisindolo[2',3':3,4]pyrido[2,1-a:2',1'-g][2,7]naphthyridine-7-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Guidance literature:
Neben 26, 11 mit Diisobutylaluminiumhydrid;
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