methyl 1-[4-(2-{5-benzylhexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctanecarboxylate

Base Information

Chemical Name:methyl 1-[4-(2-{5-benzylhexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctanecarboxylate
CAS No.:1258304-79-8
Molecular Formula:C₃₅H₄₇N₅O₂
Molecular Weight:569.79
Hs Code.:

Synonyms:methyl 1-[4-(2-{5-benzylhexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctanecarboxylate

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Chemical Property of methyl 1-[4-(2-{5-benzylhexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctanecarboxylate

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Technology Process of methyl 1-[4-(2-{5-benzylhexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctanecarboxylate

There total 1 articles about methyl 1-[4-(2-{5-benzylhexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 1258304-78-7
methyl 1-[4-(2-chloro-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctanecarboxylate

: 86732-22-1
2-benzyloctahydropyrrolo[3,4-c]pyrrole

: 1258304-79-8
methyl 1-[4-(2-{5-benzylhexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctanecarboxylate

Guidance literature:: In methanol; at 120 ℃; for 86h; Inert atmosphere;
DOI:10.1016/j.bmc.2010.07.034

Reference yield: 96.0%

: 1258304-79-8
methyl 1-[4-(2-{5-benzylhexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctanecarboxylate

: 1258304-80-1
{1-[4-(2-{5-benzylhexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol

Guidance literature:: methyl 1-[4-(2-{5-benzylhexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctanecarboxylate; With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃; for 16h; Inert atmosphere;

With water; In diethyl ether; ethyl acetate; at 0 - 20 ℃; for 1.16667h;
DOI:10.1016/j.bmc.2010.07.034