Technology Process of C30H39N
There total 15 articles about C30H39N which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1-{4-[α-(1-tricyclo[3.3.1.13,7]decyl)phenylmethyl]phenylacetyl}pirerazine;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 3h;
Reflux;
With
sodium hydroxide;
In
tetrahydrofuran; ethanol; water;
at 0 ℃;
DOI:10.1021/jm3013008
- Guidance literature:
-
α-{4-[2-(1-piperidinyl)ethyl]phenyl}-α-phenyl-1-tricyclo[3.3.1.13,7]decanemethanol;
With
trifluoroacetic acid;
In
dichloromethane;
at 20 ℃;
for 0.25h;
Inert atmosphere;
With
triethylsilane;
In
dichloromethane;
at 20 ℃;
for 1h;
Inert atmosphere;
With
sodium carbonate;
In
dichloromethane; water;
at 0 ℃;
Inert atmosphere;
DOI:10.1021/jm3013008
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: n-butyllithium / tetrahydrofuran; hexane; N,N-dimethyl-formamide / 2 h / -80 - 20 °C / Inert atmosphere
1.2: 0 °C / Inert atmosphere
2.1: potassium tert-butylate / 1,2-dimethoxyethane; methanol / 2 h / -60 - 80 °C / Inert atmosphere
3.1: hydrogenchloride; water / 3 h / Reflux
4.1: sodium hydroxide / ethanol; water / 2 h / Reflux
4.2: 0 °C
5.1: thionyl chloride / 1 h / 60 °C
6.1: tetrahydrofuran / 12 h / 0 - 20 °C / Reflux
7.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / Reflux
7.2: 0 °C
With
hydrogenchloride; lithium aluminium tetrahydride; n-butyllithium; thionyl chloride; potassium tert-butylate; water; sodium hydroxide;
In
tetrahydrofuran; methanol; 1,2-dimethoxyethane; ethanol; hexane; water; N,N-dimethyl-formamide;
DOI:10.1021/jm3013008
![1-{4-[α-(1-tricyclo[3.3.1.1<sup>3,7</sup>]decyl)phenylmethyl]phenylacetyl}pirerazine](/Databaselist/images/loading.webp)
