(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

Base Information

Chemical Name:(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester
CAS No.:75685-17-5
Molecular Formula:C₃₂H₄₄O₆Si
Molecular Weight:552.783
Hs Code.:

Synonyms:(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

Suppliers and Price of (Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

There total 11 articles about (Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2946-01-2
(3aR,5R,6S,6aR)-5-((R)-1,2-dihydroxyethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-yl 4-methylbenzenesulfonate

: 75685-17-5
(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: p-toluenesulfonic acid / 0.5 h / Heating

2: 65 percent / soda lime / benzene / 225 - 235 °C / 5 Torr

3: hydrogen / 5 percent Pd/C / ethyl acetate / 0.17 h

4: 1.) p-toluenesulfonyl chloride, pyridine, 2.) 1 N KOH / 1.) CH₂Cl₂, 0 deg C, 3 h; room temperature, 20 h, 2.) MeOH/H₂O, 0 deg C

5: 1.) n-BuLi / hexamethylphosphoric acid triamide; hexane / 1.) 5 deg C, 2.) room temperature, 20 h

6: diethyl ether

7: hydrogen, ethylene diamine / nickel acetate, sodium borohydride / ethanol; H₂O

8: imidazole / dimethylformamide / 17 h / 78 °C

With pyridine; 1H-imidazole; potassium hydroxide; n-butyllithium; soda lime; hydrogen; toluene-4-sulfonic acid; ethylenediamine; p-toluenesulfonyl chloride; sodium tetrahydroborate; palladium on activated charcoal; nickel diacetate; In N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether; ethanol; hexane; water; ethyl acetate; N,N-dimethyl-formamide; benzene;

Reference yield:

: 75646-86-5
1,2-O-isopropylidene-5,6-O-methoxymethylidene-3-deoxy-D-erythro-3,4-hexofuranoside

: 75685-17-5
(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: hydrogen / 5 percent Pd/C / ethyl acetate / 0.17 h

2: 1.) p-toluenesulfonyl chloride, pyridine, 2.) 1 N KOH / 1.) CH₂Cl₂, 0 deg C, 3 h; room temperature, 20 h, 2.) MeOH/H₂O, 0 deg C

3: 1.) n-BuLi / hexamethylphosphoric acid triamide; hexane / 1.) 5 deg C, 2.) room temperature, 20 h

4: diethyl ether

5: hydrogen, ethylene diamine / nickel acetate, sodium borohydride / ethanol; H₂O

6: imidazole / dimethylformamide / 17 h / 78 °C

With pyridine; 1H-imidazole; potassium hydroxide; n-butyllithium; hydrogen; ethylenediamine; p-toluenesulfonyl chloride; sodium tetrahydroborate; palladium on activated charcoal; nickel diacetate; In N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether; ethanol; hexane; water; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 75646-85-4
3-p-toluenesulphonate of 1,2-O-isopropylidene-5,6-O-methoxymethylidene-α-D-glucofuranose

: 75685-17-5
(Z)-(R)-8-(tert-Butyl-diphenyl-silanyloxy)-8-((3aR,5R,6aR)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-oct-5-enoic acid methyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: 65 percent / soda lime / benzene / 225 - 235 °C / 5 Torr

2: hydrogen / 5 percent Pd/C / ethyl acetate / 0.17 h

3: 1.) p-toluenesulfonyl chloride, pyridine, 2.) 1 N KOH / 1.) CH₂Cl₂, 0 deg C, 3 h; room temperature, 20 h, 2.) MeOH/H₂O, 0 deg C

4: 1.) n-BuLi / hexamethylphosphoric acid triamide; hexane / 1.) 5 deg C, 2.) room temperature, 20 h

5: diethyl ether

6: hydrogen, ethylene diamine / nickel acetate, sodium borohydride / ethanol; H₂O

7: imidazole / dimethylformamide / 17 h / 78 °C

With pyridine; 1H-imidazole; potassium hydroxide; n-butyllithium; soda lime; hydrogen; ethylenediamine; p-toluenesulfonyl chloride; sodium tetrahydroborate; palladium on activated charcoal; nickel diacetate; In N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether; ethanol; hexane; water; ethyl acetate; N,N-dimethyl-formamide; benzene;