N-(2-aminophenyl)-4-tert-butylbenzamide

Base Information

Chemical Name:N-(2-aminophenyl)-4-tert-butylbenzamide
CAS No.:219492-28-1
Molecular Formula:C₁₇H₂₀N₂O
Molecular Weight:268.359
Hs Code.:
DSSTox Substance ID:DTXSID80360659
Wikidata:Q82142517
Mol file:219492-28-1.mol

Synonyms:N-(2-aminophenyl)-4-tert-butylbenzamide;219492-28-1;N-(2-Aminophenyl)-4-(tert-butyl)benzamide;SCHEMBL5223727;DTXSID80360659;WNUQREGTGZRIBN-UHFFFAOYSA-N;AKOS000132497;N2-(4-t-butylbenzoyl)-1,2-benzenediamine;EN300-31741;N1-(4-tert-butylbenzoyl)-1,2-benzenediamine;J-014367;Z239120436

Suppliers and Price of N-(2-aminophenyl)-4-tert-butylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-(2-AMINOPHENYL)-4-TERT-BUTYLBENZAMIDE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
N-(2-AMINOPHENYL)-4-TERT-BUTYLBENZAMIDE 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
N-(2-AMINOPHENYL)-4-TERT-BUTYLBENZAMIDE 95.00%
1G
$ 852.55

AK Scientific
N-(2-Aminophenyl)-4-tert-butylbenzamide
1g
$ 503.00

Total 2 raw suppliers

Chemical Property of N-(2-aminophenyl)-4-tert-butylbenzamide

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:268.157563266
Heavy Atom Count:20
Complexity:326

Purity/Quality:

97% ^*data from raw suppliers

N-(2-AMINOPHENYL)-4-TERT-BUTYLBENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C1=CC=C(C=C1)C(=O)NC2=CC=CC=C2N
Uses N-(2-aminophenyl)-4-tert-butylbenzamide is a reactant in preparation of dibenzamidobenzene inhibitors of human factor Xa.

Technology Process of N-(2-aminophenyl)-4-tert-butylbenzamide

There total 3 articles about N-(2-aminophenyl)-4-tert-butylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 88-74-4
2-nitro-aniline

: 219492-28-1
N-(2-aminophenyl)-4-(1,1-dimethylethyl)-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / CH₂Cl₂

2: 79 percent / H₂ / Pd/C / tetrahydrofuran / 12 h

With pyridine; hydrogen; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; 1: Acylation / 2: Hydrogenation;
DOI:10.1021/jm990326m

Reference yield:

: 1710-98-1
p-tert-butyl benzoyl chloride

: 219492-28-1
N-(2-aminophenyl)-4-(1,1-dimethylethyl)-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / CH₂Cl₂

2: 79 percent / H₂ / Pd/C / tetrahydrofuran / 12 h

With pyridine; hydrogen; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; 1: Acylation / 2: Hydrogenation;
DOI:10.1021/jm990326m