4-(2-Butoxycarbonylmethoxy-ethyl)-piperazine-1-carboxylic acid benzyl ester

Base Information

Chemical Name:4-(2-Butoxycarbonylmethoxy-ethyl)-piperazine-1-carboxylic acid benzyl ester
CAS No.:181119-68-6
Molecular Formula:C₂₀H₃₀N₂O₅
Molecular Weight:378.469
Hs Code.:

Synonyms:4-(2-Butoxycarbonylmethoxy-ethyl)-piperazine-1-carboxylic acid benzyl ester

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Chemical Property of 4-(2-Butoxycarbonylmethoxy-ethyl)-piperazine-1-carboxylic acid benzyl ester

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Technology Process of 4-(2-Butoxycarbonylmethoxy-ethyl)-piperazine-1-carboxylic acid benzyl ester

There total 1 articles about 4-(2-Butoxycarbonylmethoxy-ethyl)-piperazine-1-carboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 31166-44-6
phenylmethyl 1-piperazinecarboxylate

: 68448-72-6
2-Chlor-aethoxyesssigsaeure-butylester

: 181119-68-6
4-(2-Butoxycarbonylmethoxy-ethyl)-piperazine-1-carboxylic acid benzyl ester

Guidance literature:: With sodium carbonate; sodium iodide; In various solvent(s); Heating;
DOI:10.1016/0040-4039(96)00964-1

Reference yield:

: 181119-68-6
4-(2-Butoxycarbonylmethoxy-ethyl)-piperazine-1-carboxylic acid benzyl ester

: 130018-87-0,163837-48-7
(+)-Cetirizine dihydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / H₂ / 10percent Pd-C / ethyl acetate / 760 Torr

3: 86 percent / 2M HCl / 4 h / 50 °C

With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethyl acetate;
DOI:10.1016/0040-4039(96)00964-1

Reference yield:

: 181119-68-6
4-(2-Butoxycarbonylmethoxy-ethyl)-piperazine-1-carboxylic acid benzyl ester

: 181119-59-5
(2-{4-[(S)-(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-ethoxy)-acetic acid butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / H₂ / 10percent Pd-C / ethyl acetate / 760 Torr

With hydrogen; palladium on activated charcoal; In ethyl acetate;
DOI:10.1016/0040-4039(96)00964-1