5-[2-amino-4-(3-bromo-4-fluorophenyI)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yI]-2-ethyIphenyl methanesulfonate

Base Information

Chemical Name:5-[2-amino-4-(3-bromo-4-fluorophenyI)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yI]-2-ethyIphenyl methanesulfonate
CAS No.:1035268-13-3
Molecular Formula:C₁₉H₁₉BrFN₃O₄S
Molecular Weight:484.346
Hs Code.:

Synonyms:5-[2-amino-4-(3-bromo-4-fluorophenyI)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yI]-2-ethyIphenyl methanesulfonate

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Chemical Property of 5-[2-amino-4-(3-bromo-4-fluorophenyI)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yI]-2-ethyIphenyl methanesulfonate

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Technology Process of 5-[2-amino-4-(3-bromo-4-fluorophenyI)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yI]-2-ethyIphenyl methanesulfonate

There total 1 articles about 5-[2-amino-4-(3-bromo-4-fluorophenyI)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yI]-2-ethyIphenyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1035268-12-2
5-[4-(3-bromo-4-fluorophenyl)-1-methyl-5-oxo-2-thioxoimidazolidin-4-yl]-2-ethylphenyl methanesulfonate

: 1035268-13-3
5-[2-amino-4-(3-bromo-4-fluorophenyI)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yI]-2-ethyIphenyl methanesulfonate

Guidance literature:: With tert.-butylhydroperoxide; ammonia; In methanol; water; at 35 ℃; for 2.5h;

Reference yield: 15.0%

: 1035268-13-3
5-[2-amino-4-(3-bromo-4-fluorophenyI)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yI]-2-ethyIphenyl methanesulfonate

: 109299-78-7
pyrimidine 5-boronic acid

: 1035268-14-4
5-[2-amino-4-(4-fluoro-3-pyrimidin-5-ylphenyl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yl]-2-ethylphenyl methanesulfonate

Guidance literature:: With potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In tetrahydrofuran; water; at 130 ℃; for 0.75h; Irradiation in a microwave;