N-[2-[4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetylamino]-5-methoxyphenyl]-N-methylcarbamic acid t-butyl ester

Base Information

Chemical Name:N-[2-[4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetylamino]-5-methoxyphenyl]-N-methylcarbamic acid t-butyl ester
CAS No.:314271-25-5
Molecular Formula:C₂₅H₂₉N₃O₇S
Molecular Weight:515.587
Hs Code.:

Synonyms:N-[2-[4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetylamino]-5-methoxyphenyl]-N-methylcarbamic acid t-butyl ester

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Chemical Property of N-[2-[4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetylamino]-5-methoxyphenyl]-N-methylcarbamic acid t-butyl ester

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Technology Process of N-[2-[4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetylamino]-5-methoxyphenyl]-N-methylcarbamic acid t-butyl ester

There total 2 articles about N-[2-[4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetylamino]-5-methoxyphenyl]-N-methylcarbamic acid t-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 314271-24-4
N-(2-amino-5-methoxyphenyl)-N-methylcarbamic acid t-butyl ester

: 179087-93-5
[4-[[2,4-dioxo-1,3-thiazolidine-5-yl]methyl]phenoxy]acetic acid

: 314271-25-5
N-[2-[4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetylamino]-5-methoxyphenyl]-N-methylcarbamic acid t-butyl ester

Guidance literature:: [4-[[2,4-dioxo-1,3-thiazolidine-5-yl]methyl]phenoxy]acetic acid; With thionyl chloride; N,N-dimethyl-formamide; In dichloromethane; at 39 ℃; for 0.5 - 6h; Heating / reflux;

N-(2-amino-5-methoxyphenyl)-N-methylcarbamic acid t-butyl ester; With triethylamine; In dichloromethane; at 0 - 5 ℃; for 1 - 1.25h; Product distribution / selectivity;