Technology Process of C35H36N4O5
There total 9 articles about C35H36N4O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane;
at 20 ℃;
for 18h;
DOI:10.1021/ol300599p
- Guidance literature:
-
Multi-step reaction with 7 steps
1: trichlorophosphate / N,N-dimethyl-formamide / 1.58 h / 0 - 35 °C
2: ammonium acetate / 1 h / Inert atmosphere; Reflux
3: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h / 0 °C / Reflux
4: 1,1'-carbonyldiimidazole / tetrahydrofuran; dichloromethane / 0 - 20 °C
5: acetic acid / tetrahydrofuran / 40 °C
6: triethylamine; p-toluenesulfonyl chloride / dichloromethane / 6 h / 0 - 20 °C
7: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 18 h / 20 °C
With
dmap; lithium aluminium tetrahydride; ammonium acetate; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; p-toluenesulfonyl chloride; 1,1'-carbonyldiimidazole; trichlorophosphate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ol300599p
- Guidance literature:
-
Multi-step reaction with 6 steps
1: ammonium acetate / 1 h / Inert atmosphere; Reflux
2: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h / 0 °C / Reflux
3: 1,1'-carbonyldiimidazole / tetrahydrofuran; dichloromethane / 0 - 20 °C
4: acetic acid / tetrahydrofuran / 40 °C
5: triethylamine; p-toluenesulfonyl chloride / dichloromethane / 6 h / 0 - 20 °C
6: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 18 h / 20 °C
With
dmap; lithium aluminium tetrahydride; ammonium acetate; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; p-toluenesulfonyl chloride; 1,1'-carbonyldiimidazole;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/ol300599p