5-(bis(2-chloroethyl)amino)-1-methylbenzimidazolyl-2-acetic acid methyl ester

Base Information

Chemical Name:5-(bis(2-chloroethyl)amino)-1-methylbenzimidazolyl-2-acetic acid methyl ester
CAS No.:134426-36-1
Molecular Formula:C₁₅H₁₉Cl₂N₃O₂
Molecular Weight:344.241
Hs Code.:
Mol file:134426-36-1.mol

Synonyms:5-(bis(2-chloroethyl)amino)-1-methylbenzimidazolyl-2-acetic acid methyl ester

Suppliers and Price of 5-(bis(2-chloroethyl)amino)-1-methylbenzimidazolyl-2-acetic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 5-(bis(2-chloroethyl)amino)-1-methylbenzimidazolyl-2-acetic acid methyl ester

Chemical Property:

Vapor Pressure:1.67E-10mmHg at 25°C
Boiling Point:509.6°Cat760mmHg
Flash Point:262°C
PSA：47.36000
Density:1.3g/cm³
LogP:2.57280

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-(bis(2-chloroethyl)amino)-1-methylbenzimidazolyl-2-acetic acid methyl ester

There total 5 articles about 5-(bis(2-chloroethyl)amino)-1-methylbenzimidazolyl-2-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 134426-35-0
<5--1-methyl-benzimidazolyl-(2)>ethansaeuremethylester

: 134426-36-1
<5--1-methyl-benzimidazolyl-(2)>ethansaeuremethylester

Guidance literature:: With thionyl chloride; In chloroform; 1.) overnight, 2.) 1 h, 40 deg C;

Reference yield:

: 134426-32-7
<1-Methyl-5-nitro-benzimidazolyl-(2)>acetonitril

: 134426-36-1
<5--1-methyl-benzimidazolyl-(2)>ethansaeuremethylester

Guidance literature:: Multi-step reaction with 4 steps

1: 89 percent / HCl / 3.5 h / Heating

2: 57 percent / H₂ / Raney-Ni / methanol / 2 h / 45 °C / 760 Torr

3: 43 percent / acetic acid; H₂O / 20 °C

4: 58 percent / SOCl₂ / CHCl₃ / 1.) overnight, 2.) 1 h, 40 deg C

With hydrogenchloride; thionyl chloride; hydrogen; nickel; In methanol; chloroform; water; acetic acid;

Reference yield:

: 134426-33-8
<1-Methyl-5-nitro-benzimidazolyl-(2)>ethansaeuremethylester

: 134426-36-1
<5--1-methyl-benzimidazolyl-(2)>ethansaeuremethylester

Guidance literature:: Multi-step reaction with 3 steps

1: 57 percent / H₂ / Raney-Ni / methanol / 2 h / 45 °C / 760 Torr

2: 43 percent / acetic acid; H₂O / 20 °C

3: 58 percent / SOCl₂ / CHCl₃ / 1.) overnight, 2.) 1 h, 40 deg C

With thionyl chloride; hydrogen; nickel; In methanol; chloroform; water; acetic acid;