2-[4-[4-(Dimethylaminomethyl)benzoyl]benzyl]thio-3,5-dimethyl-4(3H)-quinazolinone hydrochloride

Base Information

Chemical Name:2-[4-[4-(Dimethylaminomethyl)benzoyl]benzyl]thio-3,5-dimethyl-4(3H)-quinazolinone hydrochloride
CAS No.:183166-48-5
Molecular Formula:C₂₇H₂₇N₃O₂S*ClH
Molecular Weight:494.057
Hs Code.:

Synonyms:2-[4-[4-(Dimethylaminomethyl)benzoyl]benzyl]thio-3,5-dimethyl-4(3H)-quinazolinone hydrochloride

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Chemical Property of 2-[4-[4-(Dimethylaminomethyl)benzoyl]benzyl]thio-3,5-dimethyl-4(3H)-quinazolinone hydrochloride

Chemical Property:

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Technology Process of 2-[4-[4-(Dimethylaminomethyl)benzoyl]benzyl]thio-3,5-dimethyl-4(3H)-quinazolinone hydrochloride

There total 3 articles about 2-[4-[4-(Dimethylaminomethyl)benzoyl]benzyl]thio-3,5-dimethyl-4(3H)-quinazolinone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

aqueous dimethylamine: aqueous dimethylamine

: 183170-39-0
2-mercapto-3,5-dimethylquinazolin-4-one

: 31352-40-6
bis(4-bromomethylphenyl)methanone

: 183166-48-5
2-[4-[4-(Dimethylaminomethyl)benzoyl]benzyl]thio-3,5-dimethyl-4(3H)-quinazolinone hydrochloride

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; EtOH (15.0 ml)-THF; ethyl acetate;

Reference yield:

: 13506-76-8
2-methyl-6-nitrobenzoic acid

: 183166-48-5
2-[4-[4-(Dimethylaminomethyl)benzoyl]benzyl]thio-3,5-dimethyl-4(3H)-quinazolinone hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: palladium

2: ethanol

3: sodium hydroxide / tetrahydrofuran; EtOH (15.0 ml)-THF; ethyl acetate

With sodium hydroxide; palladium; In tetrahydrofuran; EtOH (15.0 ml)-THF; ethanol; ethyl acetate;

Reference yield:

: 4389-50-8
2-amino-6-methylbenzoic acid

: 183166-48-5
2-[4-[4-(Dimethylaminomethyl)benzoyl]benzyl]thio-3,5-dimethyl-4(3H)-quinazolinone hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol

2: sodium hydroxide / tetrahydrofuran; EtOH (15.0 ml)-THF; ethyl acetate

With sodium hydroxide; In tetrahydrofuran; EtOH (15.0 ml)-THF; ethanol; ethyl acetate;