Hexahydrosiladifenidol

Base Information

Chemical Name:Hexahydrosiladifenidol
CAS No.:98299-40-2
Molecular Formula:C20H33 N O Si
Molecular Weight:331.574
Hs Code.:2933399090
European Community (EC) Number:635-538-0
UNII:LXZ2G00X0W
DSSTox Substance ID:DTXSID20913340
Nikkaji Number:J128.591B
Wikidata:Q27077980
Pharos Ligand ID:SZYDA6B72CPT
ChEMBL ID:CHEMBL3545990
Mol file:98299-40-2.mol

Synonyms:hexahydro-sila-diphenidol;hexahydrosiladifenidol;hexahydrosiladiphenidol;HHSi-difenidol;HHSiD

Suppliers and Price of Hexahydrosiladifenidol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
HHID 95.00%
5MG
$ 504.87

Total 4 raw suppliers

Chemical Property of Hexahydrosiladifenidol

Chemical Property:

Vapor Pressure:7.14E-09mmHg at 25°C
Boiling Point:449.7°Cat760mmHg
PKA:13.91±0.20(Predicted)
Flash Point:225.8°C
PSA：23.47000
Density:1.03g/cm³
LogP:3.97960
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:331.233141211
Heavy Atom Count:23
Complexity:333

Purity/Quality:

97% ^*data from raw suppliers

HHID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20/21/22
Safety Statements: 36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)[Si](CCCN2CCCCC2)(C3=CC=CC=C3)O

Technology Process of Hexahydrosiladifenidol

There total 6 articles about Hexahydrosiladifenidol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100069-71-4
Cyclohexyl(methoxy)phenyl(3-piperidinopropyl)silan

: 98299-40-2
Cyclohexylphenyl(3-piperidinopropyl)silanol

Guidance literature:: With hydrogenchloride; In isopropyl alcohol; for 16h; Yield given; Ambient temperature;
DOI:10.1002/jlac.198519851112

Reference yield:

: 110-89-4
piperidine

: 98299-40-2
Cyclohexylphenyl(3-piperidinopropyl)silanol

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / methanol / 16 h / Heating

2: 0.5N HCl / propan-2-ol / 16 h / Ambient temperature

With hydrogenchloride; In methanol; isopropyl alcohol;
DOI:10.1002/jlac.198519851112

Reference yield:

: 931-51-1
cyclohexylmagnesiumchloride

: 98299-40-2
Cyclohexylphenyl(3-piperidinopropyl)silanol

Guidance literature:: Multi-step reaction with 4 steps

1: 71 percent / diethyl ether / 1.) 15h, room temperature, 2.) 4h, reflux

2: 87 percent / benzene; diethyl ether / 4 h / Heating

3: 96 percent / methanol / 16 h / Heating

4: 0.5N HCl / propan-2-ol / 16 h / Ambient temperature

With hydrogenchloride; In methanol; diethyl ether; isopropyl alcohol; benzene;
DOI:10.1002/jlac.198519851112