Technology Process of dimethyl 8-oxo-4-(1-phenylvinyl)spiro[4.5]deca-6,9-diene-2,2-dicarboxylate
There total 8 articles about dimethyl 8-oxo-4-(1-phenylvinyl)spiro[4.5]deca-6,9-diene-2,2-dicarboxylate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate; triphenylphosphine; bis(dibenzylideneacetone)-palladium(0);
In
N,N-dimethyl-formamide;
at 90 ℃;
for 3h;
Solvent;
Temperature;
Concentration;
Inert atmosphere;
DOI:10.1002/adsc.201300326
- Guidance literature:
-
With
C34H26O; potassium carbonate; bis(dibenzylideneacetone)-palladium(0);
In
N,N-dimethyl-formamide;
at 90 ℃;
for 18h;
Reagent/catalyst;
Inert atmosphere;
DOI:10.1002/adsc.201300326
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere
1.2: 1 h / 20 °C / Inert atmosphere
2.1: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
3.1: bis(dibenzylideneacetone)-palladium(0); potassium carbonate; C34H26O / N,N-dimethyl-formamide / 18 h / 90 °C / Inert atmosphere
With
C34H26O; tetrabutyl ammonium fluoride; sodium hydride; potassium carbonate; acetic acid; bis(dibenzylideneacetone)-palladium(0);
In
tetrahydrofuran; N,N-dimethyl-formamide; mineral oil;
DOI:10.1002/adsc.201300326
