2,5-anhydro-3,4:6,7-bis-O-(1-methylethylidene)-1-deoxy-1-(3-aminophenyl)-D-glycero-L-galacto-heptitol

Base Information

• Chemical Name: 2,5-anhydro-3,4:6,7-bis-O-(1-methylethylidene)-1-deoxy-1-(3-aminophenyl)-D-glycero-L-galacto-heptitol
• CAS No.: 1198465-38-1
• Molecular Formula: C₁₉H₂₇NO₅
• Molecular Weight: 349.427

Synonyms:2,5-anhydro-3,4:6,7-bis-O-(1-methylethylidene)-1-deoxy-1-(3-aminophenyl)-D-glycero-L-galacto-heptitol

Chemical Property of 2,5-anhydro-3,4:6,7-bis-O-(1-methylethylidene)-1-deoxy-1-(3-aminophenyl)-D-glycero-L-galacto-heptitol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5-anhydro-3,4:6,7-bis-O-(1-methylethylidene)-1-deoxy-1-(3-aminophenyl)-D-glycero-L-galacto-heptitol

There total 3 articles about 2,5-anhydro-3,4:6,7-bis-O-(1-methylethylidene)-1-deoxy-1-(3-aminophenyl)-D-glycero-L-galacto-heptitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

(6Z)-3,6-anhydro-1,2:4,5-bis-O-(1-methylethylidene)-7-bromo-7-deoxy-7-(3-nitrophenyl)-L-gluco-hept-6-enitol (1198465-29-0) → 2,5-anhydro-3,4:6,7-bis-O-(1-methylethylidene)-1-deoxy-1-(3-aminophenyl)-D-glycero-L-galacto-heptitol (1198465-38-1)

Guidance literature:

With hydrogen; In ethyl acetate; at 20 ℃; under 7500.75 Torr;

DOI:10.1016/j.tetlet.2009.09.019

Reference yield:

m-nitrobenzene boronic acid (13331-27-6) → 2,5-anhydro-3,4:6,7-bis-O-(1-methylethylidene)-1-deoxy-1-(3-aminophenyl)-D-glycero-L-galacto-heptitol (1198465-38-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium carbonate / 1,2-dimethoxyethane; water / 0.17 h

1.2: 24 h / 85 °C

2.1: hydrogen / ethyl acetate / 7500.75 Torr

With hydrogen; potassium carbonate; In 1,2-dimethoxyethane; water; ethyl acetate; 1.2: Suzuki coupling;

DOI:10.1002/ejoc.201100949

Reference yield:

(3aR,6S,6aR)-4-Dibromomethylene-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole → 2,5-anhydro-3,4:6,7-bis-O-(1-methylethylidene)-1-deoxy-1-(3-aminophenyl)-D-glycero-L-galacto-heptitol (1198465-38-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium carbonate / 1,2-dimethoxyethane; water / 0.17 h

1.2: 24 h / 85 °C

2.1: hydrogen / ethyl acetate / 7500.75 Torr

With hydrogen; potassium carbonate; In 1,2-dimethoxyethane; water; ethyl acetate; 1.2: Suzuki coupling;

DOI:10.1002/ejoc.201100949

upstream raw materials:

(6Z)-3,6-anhydro-1,2:4,5-bis-O-(1-methylethylidene)-7-bromo-7-deoxy-7-(3-nitrophenyl)-L-gluco-hept-6-enitol

m-nitrobenzene boronic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1198465-38-1 2,5-anhydro-3,4:6,7-bis-O-(1-methylethylidene)-1-deoxy-1-(3-aminophenyl)-D-glycero-L-galacto-heptitol

Send

Send

Metric Ton KG G Pound L ML

Send

Send