trifluoroacetic acid salt of L-alanine ethyl thioester

Base Information

• Chemical Name: trifluoroacetic acid salt of L-alanine ethyl thioester
• CAS No.: 1454706-29-6
• Molecular Formula: C₂HF₃O₂*C₅H₁₁NOS
• Molecular Weight: 247.238
• Mol file: 1454706-29-6.mol

Synonyms:trifluoroacetic acid salt of L-alanine ethyl thioester

Chemical Property of trifluoroacetic acid salt of L-alanine ethyl thioester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trifluoroacetic acid salt of L-alanine ethyl thioester

There total 1 articles about trifluoroacetic acid salt of L-alanine ethyl thioester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

trifluoroacetic acid (76-05-1) + (S)-S-ethyl 2-((tert-butoxycarbonyl)amino)propanethioate (292150-92-6) → trifluoroacetic acid salt of L-alanine ethyl thioester (1454706-29-6)

Guidance literature:

In dichloromethane; at 0 - 20 ℃; for 1.25h;

DOI:10.1021/jacs.9b02554

Reference yield:

trifluoroacetic acid salt of L-alanine ethyl thioester (1454706-29-6) → L-alanin (56-41-7,25191-17-7,18875-37-1)

Guidance literature:

With water; In aq. phosphate buffer; at 25 ℃; pH=7.5; Kinetics;

DOI:10.1021/jacs.9b02554

Reference yield:

trifluoroacetic acid salt of L-alanine ethyl thioester (1454706-29-6) + (((R)-1-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)phenoxyphosphonyl chloride → S-ethyl (2S)-2-[[[(1R)-2-(6-aminopurin-9-yl)-1-methylethoxy]methylphenoxyphosphoryl]amino]propanethioate

Guidance literature:

With triethylamine; In dichloromethane; at -50 - 30 ℃; for 1h; Inert atmosphere;

upstream raw materials:

trifluoroacetic acid

(S)-S-ethyl 2-((tert-butoxycarbonyl)amino)propanethioate

Downstream raw materials:

L-alanin