4-(2-Pyridylazo)-N,N-dimethylaniline

Base Information

• Chemical Name: 4-(2-Pyridylazo)-N,N-dimethylaniline
• CAS No.: 13103-75-8
• Molecular Formula: C₁₃H₁₄N₄
• Molecular Weight: 226.281
• Hs Code.: 2933399090
• European Community (EC) Number: 236-026-6
• NSC Number: 9358
• DSSTox Substance ID: DTXSID00903502,DTXSID001302586
• Nikkaji Number: J208.861D
• Wikidata: Q106902735
• Pharos Ligand ID: H1MDVMZXKKZ6
• ChEMBL ID: CHEMBL1984524
• Mol file: 13103-75-8.mol

Synonyms:4-(2-pyridylazo)-N,N-dimethylaniline

Chemical Property of 4-(2-Pyridylazo)-N,N-dimethylaniline

Chemical Property:

• Vapor Pressure: 2.22E-06mmHg at 25°C
• Melting Point: 108-110°C
• Boiling Point: 392.8°Cat760mmHg
• PKA: 3.27±0.10(Predicted)
• Flash Point: 191.4°C
• PSA: 40.85000
• Density: 1.08g/cm³
• LogP: 3.56300
• Water Solubility.: 21.27mg/L(temperature not stated)
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 226.121846464
• Heavy Atom Count: 17
• Complexity: 244

Purity/Quality:

98%,99%, ^*data from raw suppliers

Pyridine-2-azo-p-dimethylaniline ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=CC=C(C=C1)N=NC2=CC=CC=N2

Technology Process of 4-(2-Pyridylazo)-N,N-dimethylaniline

There total 12 articles about 4-(2-Pyridylazo)-N,N-dimethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

2-aminopyridine (504-29-0) + p-dimethylaminonitrosobenzene (138-89-6) → pyridine-azo-p-dimethyl aniline (77038-70-1,13103-75-8,38894-49-4)

Guidance literature:

With sodium hydroxide; In benzene; at 80 ℃; for 9h;

DOI:10.1016/j.saa.2011.11.007

Reference yield:

2-aminopyridine (504-29-0) + N,N-Dimethyl-4-nitroaniline (100-23-2) → pyridine-azo-p-dimethyl aniline (77038-70-1,13103-75-8,38894-49-4)

Guidance literature:

With sodium; toluene;

DOI:10.1021/ja01154a031

Reference yield:

C24H24N6O5S2 → C11H10N2O6S2(2-) + pyridine-azo-p-dimethyl aniline (77038-70-1,13103-75-8,38894-49-4)

Guidance literature:

With phosphate buffer; water; TEM-2 β-lactamase; at 20 ℃; Rate constant; Mechanism; pH 7.5;

DOI:10.1021/ja00317a053

upstream raw materials:

2-aminopyridine

p-dimethylaminonitrosobenzene

pyridine-azo-p-dimethyl aniline

N,N-Dimethyl-4-nitroaniline

Downstream raw materials:

pyridine-azo-p-dimethyl aniline

N,N-dimethyl-4-(1-oxy-[2]pyridylazo)-aniline-N-oxide

1,1'-dihydroxy-2,2'-diphenyl-3,3'-biindole

Br^(1-)*C₁₆H₂₀BrN₄⁽¹⁺⁾