2-chloro-6-(3-fluorophenyl)-7-iodo-3-(4-methoxyphenyl)furo[2,3-b]pyrazine

Base Information

Chemical Name:2-chloro-6-(3-fluorophenyl)-7-iodo-3-(4-methoxyphenyl)furo[2,3-b]pyrazine
CAS No.:1178980-14-7
Molecular Formula:C₁₉H₁₁ClFIN₂O₂
Molecular Weight:480.664
Hs Code.:

Synonyms:2-chloro-6-(3-fluorophenyl)-7-iodo-3-(4-methoxyphenyl)furo[2,3-b]pyrazine

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Chemical Property of 2-chloro-6-(3-fluorophenyl)-7-iodo-3-(4-methoxyphenyl)furo[2,3-b]pyrazine

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Technology Process of 2-chloro-6-(3-fluorophenyl)-7-iodo-3-(4-methoxyphenyl)furo[2,3-b]pyrazine

There total 1 articles about 2-chloro-6-(3-fluorophenyl)-7-iodo-3-(4-methoxyphenyl)furo[2,3-b]pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1178980-05-6
1-(4-methoxybenzyl)-5-chloro-3-(2-(3-uorophenyl)ethynyl)-6-(4-methoxyphenyl)pyrazin-2(1H)-one

: 1178980-14-7
2-chloro-6-(3-fluorophenyl)-7-iodo-3-(4-methoxyphenyl)furo[2,3-b]pyrazine

Guidance literature:: With iodine; In dichloromethane; at 20 ℃; for 0.166667h;
DOI:10.1071/CH08376

Reference yield: 78.0%

: 1178980-14-7
2-chloro-6-(3-fluorophenyl)-7-iodo-3-(4-methoxyphenyl)furo[2,3-b]pyrazine

: 4334-88-7
p-ethoxycarbonylphenylboronic acid

: 1178980-24-9
ethyl 4-(2-chloro-6-(3-fluorophenyl)-3-(4-methoxyphenyl)furo[2,3-b]pyrazin-7-yl)benzoate

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃; regioselective reaction; Microwave irradiation;
DOI:10.1071/CH08376

Reference yield: 74.0%

: 629-05-0
n-octyne

: 1178980-14-7
2-chloro-6-(3-fluorophenyl)-7-iodo-3-(4-methoxyphenyl)furo[2,3-b]pyrazine

: 1178980-43-2
2-chloro-6-(3-fluorophenyl)-3-(4-methoxyphenyl)-7-(oct-1-ynyl)furo[2,3-b]pyrazine

: C₃₅H₃₇FN₂O₂

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In N,N-dimethyl-formamide; at 95 ℃; Microwave irradiation;
DOI:10.1071/CH08376