14-piperazinyl-3,6,10-tris(2-nitrobenzenesulfonyl)-3,6,10,16-tetraazabicyclo[10.3.1]hexadeca-1⁽¹⁶⁾,12,14-triene

Base Information

• Chemical Name: 14-piperazinyl-3,6,10-tris(2-nitrobenzenesulfonyl)-3,6,10,16-tetraazabicyclo[10.3.1]hexadeca-1⁽¹⁶⁾,12,14-triene
• CAS No.: 221298-20-0
• Molecular Formula: C₃₄H₃₇N₉O₁₂S₃
• Molecular Weight: 859.919
• Mol file: 221298-20-0.mol

Synonyms:14-piperazinyl-3,6,10-tris(2-nitrobenzenesulfonyl)-3,6,10,16-tetraazabicyclo[10.3.1]hexadeca-1⁽¹⁶⁾,12,14-triene

Chemical Property of 14-piperazinyl-3,6,10-tris(2-nitrobenzenesulfonyl)-3,6,10,16-tetraazabicyclo[10.3.1]hexadeca-1⁽¹⁶⁾,12,14-triene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 14-piperazinyl-3,6,10-tris(2-nitrobenzenesulfonyl)-3,6,10,16-tetraazabicyclo[10.3.1]hexadeca-1⁽¹⁶⁾,12,14-triene

There total 1 articles about 14-piperazinyl-3,6,10-tris(2-nitrobenzenesulfonyl)-3,6,10,16-tetraazabicyclo[10.3.1]hexadeca-1⁽¹⁶⁾,12,14-triene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

4-[3,6,10-Tris-(2-nitro-benzenesulfonyl)-3,6,10,16-tetraaza-bicyclo[10.3.1]hexadeca-1(15),12(16),13-trien-14-yl]-piperazine-1-carboxylic acid tert-butyl ester (215164-34-4) → 14-piperazinyl-3,6,10-tris(2-nitrobenzenesulfonyl)-3,6,10,16-tetraazabicyclo[10.3.1]hexadeca-1(16),12,14-triene (221298-20-0)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃;

DOI:10.1002/jhet.5570370403

Reference yield: 97.0%

1-pyrenebutyric acid (3443-45-6) + 14-piperazinyl-3,6,10-tris(2-nitrobenzenesulfonyl)-3,6,10,16-tetraazabicyclo[10.3.1]hexadeca-1(16),12,14-triene (221298-20-0) → 14-[N4-(1-pyrenebutyryl)piperazin-N1-yl]-3,6,10-tris(2-nitrobenzenesulfonyl)-3,6,10,16-tetraazabicyclo[10.3.1]hexadeca-1(16),12,14-triene (221298-24-4)

Guidance literature:

With 4-methyl-morpholine; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; acetonitrile; at 20 ℃; for 40h;

DOI:10.1002/jhet.5570370403

Reference yield: 89.0%

2-(bromomethyl)anthraquinone (7598-10-9) + 14-piperazinyl-3,6,10-tris(2-nitrobenzenesulfonyl)-3,6,10,16-tetraazabicyclo[10.3.1]hexadeca-1(16),12,14-triene (221298-20-0) → 14-[N4-(2-anthraquinonemethyl)piperazin-N1-yl]-3,6,10-tris(2-nitrobenzenesulfonyl)-3,6,10,16-tetraazabicyclo[10.3.1]hexadeca-1(16),12,14-triene (221298-22-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; acetonitrile; at 20 ℃;

DOI:10.1002/jhet.5570370403

upstream raw materials:

4-[3,6,10-Tris-(2-nitro-benzenesulfonyl)-3,6,10,16-tetraaza-bicyclo[10.3.1]hexadeca-1⁽¹⁵⁾,12⁽¹⁶⁾,13-trien-14-yl]-piperazine-1-carboxylic acid tert-butyl ester

Downstream raw materials:

14-[N⁴-(1-pyrenebutyryl)piperazin-N¹-yl]-3,6,10-tris(2-nitrobenzenesulfonyl)-3,6,10,16-tetraazabicyclo[10.3.1]hexadeca-1⁽¹⁶⁾,12,14-triene

14-[N⁴-(2-anthraquinonemethyl)piperazin-N¹-yl]-3,6,10-tris(2-nitrobenzenesulfonyl)-3,6,10,16-tetraazabicyclo[10.3.1]hexadeca-1⁽¹⁶⁾,12,14-triene