1D-(1,2,4/3,5)-2-acetamido-1,4,5-tri-O-acetyl-3-O-<(R)-1'-benzylcarboxyethyl>-1,3,4,5-cyclohexanetetrol

Base Information

Chemical Name:1D-(1,2,4/3,5)-2-acetamido-1,4,5-tri-O-acetyl-3-O-<(R)-1'-benzylcarboxyethyl>-1,3,4,5-cyclohexanetetrol
CAS No.:121788-65-6
Molecular Formula:C₂₄H₃₁NO₁₀
Molecular Weight:493.511
Hs Code.:

Synonyms:1D-(1,2,4/3,5)-2-acetamido-1,4,5-tri-O-acetyl-3-O-<(R)-1'-benzylcarboxyethyl>-1,3,4,5-cyclohexanetetrol

Suppliers and Price of 1D-(1,2,4/3,5)-2-acetamido-1,4,5-tri-O-acetyl-3-O-<(R)-1'-benzylcarboxyethyl>-1,3,4,5-cyclohexanetetrol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1D-(1,2,4/3,5)-2-acetamido-1,4,5-tri-O-acetyl-3-O-<(R)-1'-benzylcarboxyethyl>-1,3,4,5-cyclohexanetetrol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1D-(1,2,4/3,5)-2-acetamido-1,4,5-tri-O-acetyl-3-O-<(R)-1'-benzylcarboxyethyl>-1,3,4,5-cyclohexanetetrol

There total 11 articles about 1D-(1,2,4/3,5)-2-acetamido-1,4,5-tri-O-acetyl-3-O-<(R)-1'-benzylcarboxyethyl>-1,3,4,5-cyclohexanetetrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 121843-61-6
methyl 2-acetamido-4-O-acetyl-3-O-<(R)-1'-benzylcarboxyethyl>-2-deoxy-α,β-D-xylo-hex-5-enopyranoside

: 121788-65-6
1D-(1,2,4/3,5)-2-acetamido-1,4,5-tri-O-acetyl-3-O-<(R)-1'-benzylcarboxyethyl>-1,3,4,5-cyclohexanetetrol

Guidance literature:: Multi-step reaction with 2 steps

1: HgSO₄, 5 mM H₂SO₄ / dioxane; H₂O / 2 h / 80 °C

2: 1.) lithium tert-butoxyaluminium hydride / 1.) THF, 0 deg C

With sulfuric acid; mercury(II) sulfate; lithium tri-t-butoxyaluminum hydride; In 1,4-dioxane; water;
DOI:10.1021/jo00277a002

Reference yield:

: 121843-60-5
methyl 2-acetamido-4-O-acetyl-3-O-<(R)-1'-benzylcarboxyethyl>-2,6-dideoxy-6-iodo-α,β-D-glucopyranoside

: 121788-65-6
1D-(1,2,4/3,5)-2-acetamido-1,4,5-tri-O-acetyl-3-O-<(R)-1'-benzylcarboxyethyl>-1,3,4,5-cyclohexanetetrol

Guidance literature:: Multi-step reaction with 3 steps

1: AgF, pyridine

2: HgSO₄, 5 mM H₂SO₄ / dioxane; H₂O / 2 h / 80 °C

3: 1.) lithium tert-butoxyaluminium hydride / 1.) THF, 0 deg C

With pyridine; sulfuric acid; silver fluoride; mercury(II) sulfate; lithium tri-t-butoxyaluminum hydride; In 1,4-dioxane; water;
DOI:10.1021/jo00277a002

Reference yield:

: 121843-58-1
methyl 2-acetamido-3-O-<(R)-1'-benzylcarboxyethyl>-2-deoxy-α,β-D-glucopyranoside

: 121788-65-6
1D-(1,2,4/3,5)-2-acetamido-1,4,5-tri-O-acetyl-3-O-<(R)-1'-benzylcarboxyethyl>-1,3,4,5-cyclohexanetetrol

Guidance literature:: Multi-step reaction with 7 steps

1: pyridine / Ambient temperature

2: 4-dimethylaminopyridine / 18 h

3: 91 percent / KI / dimethylformamide / 1 h / 100 °C

4: 83 percent / AgF, pyridine / Ambient temperature

5: 52 percent / HgSO₄, aq. H₂SO₄ / dioxane / 2 h / 80 °C

6: lithium aluminium-tri-tert-butoxyhydride / tetrahydrofuran / 0.67 h / 0 °C

7: Et₃N, 4-dimethylaminopyridine / CH₂Cl₂ / Ambient temperature

With pyridine; dmap; sulfuric acid; silver fluoride; mercury(II) sulfate; lithium tri-t-butoxyaluminum hydride; triethylamine; potassium iodide; In tetrahydrofuran; 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)97594-5