4-(5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)benzaldehyde

Base Information

• Chemical Name: 4-(5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)benzaldehyde
• CAS No.: 1258009-57-2
• Molecular Formula: C₂₀H₂₂N₄O₃
• Molecular Weight: 366.42

Synonyms:4-(5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)benzaldehyde

Chemical Property of 4-(5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)benzaldehyde

Chemical Property:

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Technology Process of 4-(5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)benzaldehyde

There total 1 articles about 4-(5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(4-{5-[1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl]-1,2,4-oxadiazol-3-yl}phenyl)methanol (1258010-47-7) → 4-(5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)benzaldehyde (1258009-57-2)

Guidance literature:

With manganese(IV) oxide; In 1,4-dioxane; at 70 ℃;

Reference yield: 87.4%

4-(5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)benzaldehyde (1258009-57-2) + methyl (triphenylphosphoranylidene)acetate (21204-67-1,2605-67-6) → (E)-methyl 3-(4-(5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)phenyl)acrylate (1258010-08-0)

Guidance literature:

In dichloromethane; at 20 ℃;

Reference yield:

3-Amino-1,2-propanediol (616-30-8,13552-31-3,98923-21-8) + 4-(5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)benzaldehyde (1258009-57-2) → 3-(4-(5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)benzylamino)propane-1,2-diol (1258010-48-8)

Guidance literature:

With sodium cyanoborohydride; acetic acid; In methanol; at 20 ℃;

upstream raw materials:

(4-{5-[1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl]-1,2,4-oxadiazol-3-yl}phenyl)methanol

Downstream raw materials:

(E)-methyl 3-(4-(5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)phenyl)acrylate

3-(4-(5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)benzylamino)propane-1,2-diol

1-(4-{5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl}benzyl)piperidine-4-carboxylic acid

N-(4-(5-(1-cyclohexyl-5-(methoxymethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)benzyl)propan-2-amine

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