3-amino-2-biphenyl-4-yl>methyl>amino>pyridine

Base Information

Chemical Name:3-amino-2-biphenyl-4-yl>methyl>amino>pyridine
CAS No.:151323-56-7
Molecular Formula:C₄₁H₃₇N₇
Molecular Weight:627.792
Hs Code.:

3-amino-2-<N-propyl-N-<<2'-<2-(triphenylmethyl)-2H-tetrazol-5-yl>biphenyl-4-yl>methyl>amino>pyridine

Synonyms:3-amino-2-biphenyl-4-yl>methyl>amino>pyridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-amino-2-biphenyl-4-yl>methyl>amino>pyridine

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Technology Process of 3-amino-2-biphenyl-4-yl>methyl>amino>pyridine

There total 3 articles about 3-amino-2-biphenyl-4-yl>methyl>amino>pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 151323-55-6
3-nitro-2-biphenyl-4-yl>methyl>amino>pyridine

: 151323-56-7
3-amino-2-biphenyl-4-yl>methyl>amino>pyridine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; for 2h; under 3040 Torr;
DOI:10.1021/jm00070a012

Reference yield:

: 133051-88-4
N-(triphenylmethyl)-5-<4'-(bromomethyl)biphenyl-2-yl>tetrazole

: 151323-56-7
3-amino-2-biphenyl-4-yl>methyl>amino>pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 2 h / Ambient temperature

2: 88 percent / Et₃N / tetrahydrofuran / 2.5 h / Heating

3: 60 percent / H₂ / 10percent Pd/C / ethyl acetate / 2 h / 3040 Torr

With hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate;
DOI:10.1021/jm00070a012

Reference yield:

: 143618-24-0
Propyl-[2'-(2-trityl-2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amine

: 151323-56-7
3-amino-2-biphenyl-4-yl>methyl>amino>pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / Et₃N / tetrahydrofuran / 2.5 h / Heating

2: 60 percent / H₂ / 10percent Pd/C / ethyl acetate / 2 h / 3040 Torr

With hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate;
DOI:10.1021/jm00070a012