(1-adamantyl) phenylthiomethyl ketone

Base Information

• Chemical Name: (1-adamantyl) phenylthiomethyl ketone
• CAS No.: 77270-23-6
• Molecular Formula: C₁₈H₂₂OS
• Molecular Weight: 286.438
• Mol file: 77270-23-6.mol

Synonyms:(1-adamantyl) phenylthiomethyl ketone

Chemical Property of (1-adamantyl) phenylthiomethyl ketone

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (1-adamantyl) phenylthiomethyl ketone

There total 1 articles about (1-adamantyl) phenylthiomethyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1-adamantyl bromomethyl ketone (5122-82-7) + thiophenol (108-98-5) → (1-adamantyl) phenylthiomethyl ketone (77270-23-6)

Guidance literature:

With potassium carbonate; In ethanol; for 0.5h; Ambient temperature;

DOI:10.1021/jo00325a038

Reference yield: 87.0%

2-(methylthio)-1-(4-cyanophenyl)-1-ethanone (1114817-69-4) + (1-adamantyl) phenylthiomethyl ketone (77270-23-6) → 1-adamantyl (methylthio)(phenylthio)methyl ketone (1114817-90-1)

Guidance literature:

With hydridotetakis(triphenylphosphine)rhodium(I); 1,2-bis-(diphenylphosphino)ethane; In tetrahydrofuran; at 90 ℃; for 4h; Inert atmosphere;

DOI:10.1021/ol802619e

upstream raw materials:

1-adamantyl bromomethyl ketone

thiophenol

Downstream raw materials:

1-adamantyl (methylthio)(phenylthio)methyl ketone