(2R,5S,3Z)-2-benzyl-5-[N-(tert-butoxycarbonyl)amino]-4-fluoro-6-methylhept-3-enoyl (S)-sultam

Base Information

Chemical Name:(2R,5S,3Z)-2-benzyl-5-[N-(tert-butoxycarbonyl)amino]-4-fluoro-6-methylhept-3-enoyl (S)-sultam
CAS No.:919121-03-2
Molecular Formula:C₃₀H₄₃FN₂O₅S
Molecular Weight:562.746
Hs Code.:

Synonyms:(2R,5S,3Z)-2-benzyl-5-[N-(tert-butoxycarbonyl)amino]-4-fluoro-6-methylhept-3-enoyl (S)-sultam

Suppliers and Price of (2R,5S,3Z)-2-benzyl-5-[N-(tert-butoxycarbonyl)amino]-4-fluoro-6-methylhept-3-enoyl (S)-sultam

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,5S,3Z)-2-benzyl-5-[N-(tert-butoxycarbonyl)amino]-4-fluoro-6-methylhept-3-enoyl (S)-sultam

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,5S,3Z)-2-benzyl-5-[N-(tert-butoxycarbonyl)amino]-4-fluoro-6-methylhept-3-enoyl (S)-sultam

There total 2 articles about (2R,5S,3Z)-2-benzyl-5-[N-(tert-butoxycarbonyl)amino]-4-fluoro-6-methylhept-3-enoyl (S)-sultam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (2,2-difluoro-1-isopropyl-3-oxo-propyl)-carbamic acid tert-butyl ester

: 919121-03-2
(2R,5S,3Z)-2-benzyl-5-[N-(tert-butoxycarbonyl)amino]-4-fluoro-6-methylhept-3-enoyl (S)-sultam

Guidance literature:: Multi-step reaction with 2 steps

1: LiCl; (iPr)2NEt

With N-ethyl-N,N-diisopropylamine; lithium chloride; 1: Horner-Wadsworth-Emmons coupling;
DOI:10.1039/b608596b

Reference yield:

: 676460-38-1
ethyl (3S)-4-methyl-3-(N-tert-butylcarbonyloxy)amino-2,2-difluoropentanoate

: 919121-03-2
(2R,5S,3Z)-2-benzyl-5-[N-(tert-butoxycarbonyl)amino]-4-fluoro-6-methylhept-3-enoyl (S)-sultam

Guidance literature:: Multi-step reaction with 3 steps

1: DIBAl-H / -78 °C

2: LiCl; (iPr)2NEt

With diisobutylaluminium hydride; N-ethyl-N,N-diisopropylamine; lithium chloride; 2: Horner-Wadsworth-Emmons coupling;
DOI:10.1039/b608596b