3-tert-butyl-5-(4-methylpiperazin-1-yl)-N-{4-methyl-3-[6-(1H-pyrazol-4-yl)-1H-imidazo[1,2-b]-pyrazol-1-yl]phenyl}benzamide

Base Information

Chemical Name:3-tert-butyl-5-(4-methylpiperazin-1-yl)-N-{4-methyl-3-[6-(1H-pyrazol-4-yl)-1H-imidazo[1,2-b]-pyrazol-1-yl]phenyl}benzamide
CAS No.:1448315-41-0
Molecular Formula:C₃₁H₃₆N₈O
Molecular Weight:536.68
Hs Code.:

Synonyms:3-tert-butyl-5-(4-methylpiperazin-1-yl)-N-{4-methyl-3-[6-(1H-pyrazol-4-yl)-1H-imidazo[1,2-b]-pyrazol-1-yl]phenyl}benzamide

Suppliers and Price of 3-tert-butyl-5-(4-methylpiperazin-1-yl)-N-{4-methyl-3-[6-(1H-pyrazol-4-yl)-1H-imidazo[1,2-b]-pyrazol-1-yl]phenyl}benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-tert-butyl-5-(4-methylpiperazin-1-yl)-N-{4-methyl-3-[6-(1H-pyrazol-4-yl)-1H-imidazo[1,2-b]-pyrazol-1-yl]phenyl}benzamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-tert-butyl-5-(4-methylpiperazin-1-yl)-N-{4-methyl-3-[6-(1H-pyrazol-4-yl)-1H-imidazo[1,2-b]-pyrazol-1-yl]phenyl}benzamide

There total 8 articles about 3-tert-butyl-5-(4-methylpiperazin-1-yl)-N-{4-methyl-3-[6-(1H-pyrazol-4-yl)-1H-imidazo[1,2-b]-pyrazol-1-yl]phenyl}benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1448317-92-7
3-tert-butyl-N-(3-{6-[1-(4-methoxybenzyl)-1H-pyrazol-4-yl]-1H-imidazo[1,2-b]pyrazol-1-yl}-4-methylphenyl)-5-(4-methylpiperazin-1-yl)benzamide

: 1448315-41-0
3-tert-butyl-5-(4-methylpiperazin-1-yl)-N-{4-methyl-3-[6-(1H-pyrazol-4-yl)-1H-imidazo[1,2-b]-pyrazol-1-yl]phenyl}benzamide

Guidance literature:: With trifluoroacetic acid; at 80 ℃; for 3h;

Reference yield:

: 1448317-28-9
6-[1-(4-methoxybenzyl)-1H-pyrazol-4-yl]-1-(2-methyl-5-nitrophenyl)-1H-imidazo-[1,2-b]pyrazole

: 1448315-41-0
3-tert-butyl-5-(4-methylpiperazin-1-yl)-N-{4-methyl-3-[6-(1H-pyrazol-4-yl)-1H-imidazo[1,2-b]-pyrazol-1-yl]phenyl}benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: palladium 10% on activated carbon; ammonium formate / ethanol; water / 1 h / 90 °C / Microwave irradiation

2: HATU; 4-methyl-morpholine / N,N-dimethyl-formamide / 16 h / 20 °C

3: trifluoroacetic acid / 3 h / 80 °C

With 4-methyl-morpholine; palladium 10% on activated carbon; ammonium formate; HATU; trifluoroacetic acid; In ethanol; water; N,N-dimethyl-formamide;

Reference yield:

: 1448317-27-8
1-(2,2-diethoxyethyl)-1'-(4-methoxybenzyl)-N-(2-methyl-5-nitrophenyl)-1H,1'H-3,4'-bipyrazole-5-amine

: 1448315-41-0
3-tert-butyl-5-(4-methylpiperazin-1-yl)-N-{4-methyl-3-[6-(1H-pyrazol-4-yl)-1H-imidazo[1,2-b]-pyrazol-1-yl]phenyl}benzamide

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid / ethanol / 0.58 h / 120 °C / Microwave irradiation

2: palladium 10% on activated carbon; ammonium formate / ethanol; water / 1 h / 90 °C / Microwave irradiation

3: HATU; 4-methyl-morpholine / N,N-dimethyl-formamide / 16 h / 20 °C

4: trifluoroacetic acid / 3 h / 80 °C

With 4-methyl-morpholine; sulfuric acid; palladium 10% on activated carbon; ammonium formate; HATU; trifluoroacetic acid; In ethanol; water; N,N-dimethyl-formamide;