N-Boc-N-methyl-O-diphenylcarbamoyl hydroxylamine

Base Information

• Chemical Name: N-Boc-N-methyl-O-diphenylcarbamoyl hydroxylamine
• CAS No.: 934812-46-1
• Molecular Formula: C₁₉H₂₂N₂O₄
• Molecular Weight: 342.395
• Mol file: 934812-46-1.mol

Synonyms:N-Boc-N-methyl-O-diphenylcarbamoyl hydroxylamine

Chemical Property of N-Boc-N-methyl-O-diphenylcarbamoyl hydroxylamine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of N-Boc-N-methyl-O-diphenylcarbamoyl hydroxylamine

There total 1 articles about N-Boc-N-methyl-O-diphenylcarbamoyl hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

N-(tert-butoxycarbonyl)-N-methylhydroxylamine (19689-97-5) + diphenylcarbamic chloride (83-01-2) → N-Boc-N-methyl-O-diphenylcarbamoyl hydroxylamine (934812-46-1)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1055/s-2007-967990

Reference yield: 99.0%

N-Boc-N-methyl-O-diphenylcarbamoyl hydroxylamine (934812-46-1) → N-methyl-O-diphenylcarbamoyl hydroxylamine hydrochloride

Guidance literature:

In 1,4-dioxane; hydrogenchloride; at 20 ℃; for 6h;

DOI:10.1055/s-2007-967990

Reference yield:

N-Boc-N-methyl-O-diphenylcarbamoyl hydroxylamine (934812-46-1) → 2-(diphenylcarbamoyloxy) cyclohexanone

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / aq. HCl; dioxane / 6 h / 20 °C

2: 79 percent / dimethylsulfoxide / 16 h / 20 °C

In 1,4-dioxane; hydrogenchloride; dimethyl sulfoxide;

DOI:10.1055/s-2007-967990

upstream raw materials:

N-(tert-butoxycarbonyl)-N-methylhydroxylamine

diphenylcarbamic chloride

Refernces