methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-chlorobenzenecarboxylate

Base Information

Chemical Name:methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-chlorobenzenecarboxylate
CAS No.:1210047-28-1
Molecular Formula:C₂₇H₂₂ClN₅O₂
Molecular Weight:483.957
Hs Code.:

Synonyms:methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-chlorobenzenecarboxylate

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Chemical Property of methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-chlorobenzenecarboxylate

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Technology Process of methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-chlorobenzenecarboxylate

There total 2 articles about methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-chlorobenzenecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 27007-53-0
methyl-2-bromo-5-chlorobenzoate

: 1210047-26-9
4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazole-5-amine

: 1210047-28-1
methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-chlorobenzenecarboxylate

Guidance literature:: With potassium phosphate; palladium diacetate; johnphos; In toluene; for 72h; Inert atmosphere; Reflux;

Reference yield:

: 852432-98-5
(quinoxalin-6-yl)boronic acid

: 1248622-13-0
C₁₉H₁₇BrClN₃O₂

: 1210047-28-1
methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-chlorobenzenecarboxylate

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; In 1,4-dioxane; water; toluene; at 75 ℃; for 16h;
DOI:10.1016/j.bmcl.2010.07.095

Reference yield: 81.0%

: 1210047-28-1
methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-chlorobenzenecarboxylate

: 1210048-63-7
2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-chlorobenzoic acid

Guidance literature:: methyl 2-((4-(quinoxalin-6-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-chlorobenzenecarboxylate; With water; sodium hydroxide; In 1,4-dioxane; at 20 ℃;

With ammonium chloride; In water;