(R)-2-Amino-6,6,6-trifluorohexanoic acid

Base Information

• Chemical Name: (R)-2-Amino-6,6,6-trifluorohexanoic acid
• CAS No.: 120200-06-8
• Molecular Formula: C₆H₁₀F₃NO₂
• Molecular Weight: 185.146
• DSSTox Substance ID: DTXSID00426468
• Nikkaji Number: J3.221.377D
• Mol file: 120200-06-8.mol

Synonyms:(R)-2-Amino-6,6,6-trifluorohexanoic acid;120200-06-8;(2R)-2-amino-6,6,6-trifluorohexanoic acid;AC1OCSZY;SCHEMBL18762553;DTXSID00426468;RUEWGWBXZIDRJY-SCSAIBSYSA-N;D-6,6,6-TRIFLUORONORLEUCINE;(R)-2-Amino-6,6,6-trifluorohexanoicacid;CS-0513735;EN300-1299012

Chemical Property of (R)-2-Amino-6,6,6-trifluorohexanoic acid

Chemical Property:

• XLogP3: -1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 185.06636305
• Heavy Atom Count: 12
• Complexity: 157

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(CC(C(=O)O)N)CC(F)(F)F
• Isomeric SMILES: C(C[C@H](C(=O)O)N)CC(F)(F)F

Technology Process of (R)-2-Amino-6,6,6-trifluorohexanoic acid

There total 1 articles about (R)-2-Amino-6,6,6-trifluorohexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

C31H32F3N3NiO3 → C25H26N2O2 (1445869-56-6) + (D)-2-amino-6,6,6-trifluorohexanoic acid (120200-06-8)

Guidance literature:

C₃₁H₃₂F₃N₃NiO₃; With hydrogenchloride; In methanol; at 70 ℃;

With ammonium hydroxide; In water;

In water; Resolution of racemate;

DOI:10.1016/j.jfluchem.2013.02.022