2-(3-(4-acetoxyphenyl)-propenoyl-amino)-isobutyric acid 5-fluorotryptamide

Base Information

Chemical Name:2-(3-(4-acetoxyphenyl)-propenoyl-amino)-isobutyric acid 5-fluorotryptamide
CAS No.:940290-26-6
Molecular Formula:C₂₅H₂₆FN₃O₄
Molecular Weight:451.498
Hs Code.:

Synonyms:2-(3-(4-acetoxyphenyl)-propenoyl-amino)-isobutyric acid 5-fluorotryptamide

Suppliers and Price of 2-(3-(4-acetoxyphenyl)-propenoyl-amino)-isobutyric acid 5-fluorotryptamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(3-(4-acetoxyphenyl)-propenoyl-amino)-isobutyric acid 5-fluorotryptamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(3-(4-acetoxyphenyl)-propenoyl-amino)-isobutyric acid 5-fluorotryptamide

There total 3 articles about 2-(3-(4-acetoxyphenyl)-propenoyl-amino)-isobutyric acid 5-fluorotryptamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 940290-25-5
2-amino-isobutyric acid 5-fluorotryptamide

: 27542-85-4
4-acetoxycinnamic acid

: 940290-26-6
2-(3-(4-acetoxyphenyl)-propenoyl-amino)-isobutyric acid 5-fluorotryptamide

Guidance literature:: 4-acetoxycinnamic acid; With chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran; at 0 ℃; for 1h;

2-amino-isobutyric acid 5-fluorotryptamide; With triethylamine; In tetrahydrofuran; at 20 ℃; for 72h; Further stages.;
DOI:10.1016/j.bmcl.2007.02.023

Reference yield:

: 940290-24-4
2-[(benzyloxycarbonyl)amino]-isobutyric acid 5-fluorotryptamide

: 940290-26-6
2-(3-(4-acetoxyphenyl)-propenoyl-amino)-isobutyric acid 5-fluorotryptamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 92 percent / H₂ / Pd/C / methanol / 1 h / 20 °C

2.1: Et₃N; ethyl chloroformate / tetrahydrofuran / 1 h / 0 °C

2.2: 43 percent / Et₃N / tetrahydrofuran / 72 h / 20 °C

With hydrogen; chloroformic acid ethyl ester; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1016/j.bmcl.2007.02.023

Reference yield:

: 7400-08-0,50940-26-6
p-Coumaric Acid

: 940290-26-6
2-(3-(4-acetoxyphenyl)-propenoyl-amino)-isobutyric acid 5-fluorotryptamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 86 percent / pyridine / 20 °C

2.1: Et₃N; ethyl chloroformate / tetrahydrofuran / 1 h / 0 °C

2.2: 43 percent / Et₃N / tetrahydrofuran / 72 h / 20 °C

With pyridine; chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2007.02.023