Methoxy-phenyl-acetic acid (1R,2S,5R,6S)-tricyclo[4.2.1.0^2,5]non-7-en-3-yl ester

Base Information

• Chemical Name: Methoxy-phenyl-acetic acid (1R,2S,5R,6S)-tricyclo[4.2.1.0^2,5]non-7-en-3-yl ester
• CAS No.: 139157-56-5
• Molecular Formula: C₁₈H₂₀O₃
• Molecular Weight: 284.355
• Mol file: 139157-56-5.mol

Synonyms:Methoxy-phenyl-acetic acid (1R,2S,5R,6S)-tricyclo[4.2.1.0^2,5]non-7-en-3-yl ester

Chemical Property of Methoxy-phenyl-acetic acid (1R,2S,5R,6S)-tricyclo[4.2.1.0^2,5]non-7-en-3-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methoxy-phenyl-acetic acid (1R,2S,5R,6S)-tricyclo[4.2.1.0^2,5]non-7-en-3-yl ester

There total 2 articles about Methoxy-phenyl-acetic acid (1R,2S,5R,6S)-tricyclo[4.2.1.0^2,5]non-7-en-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

rac-methoxyphenylacetic acid (7021-09-2) + (1S,2R,3S,5S,6R)-Tricyclo[4.2.1.02,5]non-7-en-3-ol (136066-56-3,136173-43-8) → Methoxy-phenyl-acetic acid (1R,2S,3R,5R,6S)-tricyclo[4.2.1.02,5]non-7-en-3-yl ester (139157-56-5)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide;

DOI:10.1021/ja00545a049

Reference yield:

(S)-2-methoxy-2-phenylacetic acid (26164-26-1) + (1S,2R,3S,5S,6R)-Tricyclo[4.2.1.02,5]non-7-en-3-ol (136066-56-3,136173-43-8) → (R)-Methoxy-phenyl-acetic acid (1R,2S,3R,5R,6S)-tricyclo[4.2.1.02,5]non-7-en-3-yl ester (139157-56-5)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide;

DOI:10.1021/ja00545a049

Reference yield: 85.0%

Methoxy-phenyl-acetic acid (1R,2S,5R,6S)-tricyclo[4.2.1.02,5]non-7-en-3-yl ester (139157-56-5) → (+/-)-(E)-1-(2-methoxy-2-phenylacetoxy)-1,3-butadiene (121840-89-9)

Guidance literature:

at 450 ℃; under 0.5 - 1 Torr;

DOI:10.1016/S0957-4166(00)80037-3

upstream raw materials:

rac-methoxyphenylacetic acid

(1S,2R,3S,5S,6R)-Tricyclo[4.2.1.0^2,5]non-7-en-3-ol

(S)-2-methoxy-2-phenylacetic acid

Downstream raw materials:

(+/-)-(E)-1-(2-methoxy-2-phenylacetoxy)-1,3-butadiene

(S)-Methoxy-phenyl-acetic acid (1R,6S)-6-formyl-cyclohex-2-enyl ester

(S)-Methoxy-phenyl-acetic acid (1S,6R)-6-formyl-cyclohex-2-enyl ester

(R)-Methoxy-phenyl-acetic acid (1S,6R)-6-formyl-6-methyl-cyclohex-2-enyl ester