4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-2-ethoxybenzoic acid

Base Information

Chemical Name:4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-2-ethoxybenzoic acid
CAS No.:958227-62-8
Molecular Formula:C₂₃H₂₈F₃N₅O₄
Molecular Weight:495.502
Hs Code.:

Synonyms:4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-2-ethoxybenzoic acid

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Chemical Property of 4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-2-ethoxybenzoic acid

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Technology Process of 4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-2-ethoxybenzoic acid

There total 1 articles about 4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-2-ethoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1036488-09-1
(1S,2R)-2-(2-chloro-5-trifluoromethyl-pyrimidin-4-ylamino)-cyclopentanecarboxylic acid isopropylamide

: 59-07-4
2-ethoxy-4-aminobenzoic acid

: 958227-62-8
4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-2-ethoxybenzoic acid

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; ISOPROPYLAMIDE; at 70 ℃; for 2.5h;

Reference yield:

: 73579-08-5
Methyl-(1-methyl-[4]piperidyl)-amin

: 958227-62-8
4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-2-ethoxybenzoic acid

: 958227-71-9
2-ethoxy-4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-N-methyl-N-(1-methyl-piperidin-4-yl)-benzamide

Guidance literature:: 4-[4-((1R,2S)-2-isopropylcarbamoyl-cyclopentylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-2-ethoxybenzoic acid; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.0833333h;

Methyl-(1-methyl-[4]piperidyl)-amin; In N,N-dimethyl-formamide; at 20 ℃; for 2h;