C₂₈H₂₅IN₂O₅

Base Information

• Chemical Name: C₂₈H₂₅IN₂O₅
• CAS No.: 842164-53-8
• Molecular Formula: C₂₈H₂₅IN₂O₅
• Molecular Weight: 596.421
• Mol file: 842164-53-8.mol

Synonyms:C₂₈H₂₅IN₂O₅

Chemical Property of C₂₈H₂₅IN₂O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₂₈H₂₅IN₂O₅

There total 1 articles about C₂₈H₂₅IN₂O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1'-(7-azaindolyl)-3',5'-di-O-(p-toluoyl)-2'deoxy-D-riboside (124469-64-3) → C28H25IN2O5 (842164-53-8)

Guidance literature:

With Iodine monochloride; In dichloromethane; at 20 - 50 ℃; for 0.516667h;

DOI:10.1021/ja0009931

Reference yield:

C28H25IN2O5 (842164-53-8) → (2R,3S,5R)-2-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(3-prop-1-ynyl-pyrrolo[2,3-b]pyridin-1-yl)-tetrahydro-furan-3-ol

Guidance literature:

Multi-step reaction with 3 steps

1: 330 mg / (Ph₃P)2PdCl₂; CuI; Et₃N / 4 h / -78 - 20 °C

2: 1 M aq. NaOMe / methanol / 0.75 h

3: Et₃N; pyridine / 0.5 h / 20 °C

With pyridine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; sodium methylate; triethylamine; In methanol; 1: Heck reaction / 2: deacylation / 3: tritylation;

DOI:10.1021/ja0009931

Reference yield:

C28H25IN2O5 (842164-53-8) → Diisopropyl-phosphoramidous acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(3-prop-1-ynyl-pyrrolo[2,3-b]pyridin-1-yl)-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester

Guidance literature:

Multi-step reaction with 4 steps

1: 330 mg / (Ph₃P)2PdCl₂; CuI; Et₃N / 4 h / -78 - 20 °C

2: 1 M aq. NaOMe / methanol / 0.75 h

3: Et₃N; pyridine / 0.5 h / 20 °C

4: DMAP; Et₃N / CH₂Cl₂ / 0.25 h / 0 °C

With pyridine; dmap; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; sodium methylate; triethylamine; In methanol; dichloromethane; 1: Heck reaction / 2: deacylation / 3: tritylation / 4: Condensation;

DOI:10.1021/ja0009931

upstream raw materials:

1'-(7-azaindolyl)-3',5'-di-O-(p-toluoyl)-2'deoxy-D-riboside

Downstream raw materials:

C₃₁H₂₈N₂O₅