3-(4-fluorophenyl)-6-[2-(4-fluorophenyl)-2H-pyrazol-3-yl]imidazo[1,2-a]pyridine

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Chemical Name:3-(4-fluorophenyl)-6-[2-(4-fluorophenyl)-2H-pyrazol-3-yl]imidazo[1,2-a]pyridine
CAS No.:1612185-10-0
Molecular Formula:C₂₂H₁₄F₂N₄
Molecular Weight:372.377
Hs Code.:

Synonyms:3-(4-fluorophenyl)-6-[2-(4-fluorophenyl)-2H-pyrazol-3-yl]imidazo[1,2-a]pyridine

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Chemical Property of 3-(4-fluorophenyl)-6-[2-(4-fluorophenyl)-2H-pyrazol-3-yl]imidazo[1,2-a]pyridine

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Technology Process of 3-(4-fluorophenyl)-6-[2-(4-fluorophenyl)-2H-pyrazol-3-yl]imidazo[1,2-a]pyridine

There total 4 articles about 3-(4-fluorophenyl)-6-[2-(4-fluorophenyl)-2H-pyrazol-3-yl]imidazo[1,2-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 1612185-51-9
6-bromo-3-(4-fluorophenyl)imidazo[1,2-a]pyridine

: 1612185-45-1
1-(4-fluorophenyl)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

: 1612185-10-0
3-(4-fluorophenyl)-6-[2-(4-fluorophenyl)-2H-pyrazol-3-yl]imidazo[1,2-a]pyridine

Guidance literature:: 6-bromo-3-(4-fluorophenyl)imidazo[1,2-a]pyridine; 1-(4-fluorophenyl)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole; With sodium carbonate; In 1,2-dimethoxyethane; for 0.166667h; Inert atmosphere; Sonication;

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; for 17h; Inert atmosphere; Reflux;

Reference yield:

: 474706-74-6
6-bromo-3-iodoimidazo[1,2-a]pyridine

: 1612185-10-0
3-(4-fluorophenyl)-6-[2-(4-fluorophenyl)-2H-pyrazol-3-yl]imidazo[1,2-a]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium carbonate / 1,2-dimethoxyethane / 0.08 h / Inert atmosphere; Sonication

1.2: 17 h / Inert atmosphere; Reflux

2.1: sodium carbonate / 1,2-dimethoxyethane / 0.17 h / Inert atmosphere; Sonication

2.2: 17 h / Inert atmosphere; Reflux

With sodium carbonate; In 1,2-dimethoxyethane;

Reference yield:

: 1765-93-1
4-fluoroboronic acid

: 1612185-10-0
3-(4-fluorophenyl)-6-[2-(4-fluorophenyl)-2H-pyrazol-3-yl]imidazo[1,2-a]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium carbonate / 1,2-dimethoxyethane / 0.08 h / Inert atmosphere; Sonication

1.2: 17 h / Inert atmosphere; Reflux

2.1: sodium carbonate / 1,2-dimethoxyethane / 0.17 h / Inert atmosphere; Sonication

2.2: 17 h / Inert atmosphere; Reflux

With sodium carbonate; In 1,2-dimethoxyethane;