2-O-Acetyl-3,4,6,7-tetra-O-benzyl-L-glycero-α-D-manno-heptopyranosylchlorid

Base Information

• Chemical Name: 2-O-Acetyl-3,4,6,7-tetra-O-benzyl-L-glycero-α-D-manno-heptopyranosylchlorid
• CAS No.: 116302-70-6
• Molecular Formula: C₃₇H₃₉ClO₇
• Molecular Weight: 631.165

Synonyms:2-O-Acetyl-3,4,6,7-tetra-O-benzyl-L-glycero-α-D-manno-heptopyranosylchlorid

Chemical Property of 2-O-Acetyl-3,4,6,7-tetra-O-benzyl-L-glycero-α-D-manno-heptopyranosylchlorid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-O-Acetyl-3,4,6,7-tetra-O-benzyl-L-glycero-α-D-manno-heptopyranosylchlorid

There total 6 articles about 2-O-Acetyl-3,4,6,7-tetra-O-benzyl-L-glycero-α-D-manno-heptopyranosylchlorid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,2-O-(1-methoxy)ethylidene-3,4,6,7-tetra-O-benzyl-L-glycero-β-D-manno-heptopyranose (126456-55-1) → 2-O-Acetyl-3,4,6,7-tetra-O-benzyl-L-glycero-α-D-manno-heptopyranosylchlorid (116302-70-6)

Guidance literature:

With Vilsmeier reagent; In dichloromethane; acetonitrile; at -10 ℃; for 0.0833333h;

Reference yield:

1,2,3,4,6,7-hexa-O-acetyl-L-glycero-α-D-manno-heptopyranose (104486-80-8) → 2-O-Acetyl-3,4,6,7-tetra-O-benzyl-L-glycero-α-D-manno-heptopyranosylchlorid (116302-70-6)

Guidance literature:

Multi-step reaction with 5 steps

1: HBr / acetic acid

2: by a literature procedure

3: by a literature procedure

4: by a literature procedure

5: by a literature procedure

With hydrogen bromide; In acetic acid;

DOI:10.1016/0008-6215(89)85198-5

Reference yield:

methyl 2,3,4,6,7-penta-O-acetyl-L-glycero-α-D-manno-heptopyranoside (122622-12-2) → 2-O-Acetyl-3,4,6,7-tetra-O-benzyl-L-glycero-α-D-manno-heptopyranosylchlorid (116302-70-6)

Guidance literature:

Multi-step reaction with 6 steps

1: H₂SO₄

2: HBr / acetic acid

3: by a literature procedure

4: by a literature procedure

5: by a literature procedure

6: by a literature procedure

With sulfuric acid; hydrogen bromide; In acetic acid;

DOI:10.1016/0008-6215(89)85198-5

upstream raw materials:

1,2-O-(1-methoxy)ethylidene-3,4,6,7-tetra-O-benzyl-L-glycero-β-D-manno-heptopyranose

2,3,4,6,7-penta-O-acetyl-L-glycero-α-D-manno-heptopyranosyl bromide

methyl 2,3,4,6,7-penta-O-acetyl-L-glycero-α-D-manno-heptopyranoside

1,2,3,4,6,7-hexa-O-acetyl-L-glycero-α-D-manno-heptopyranose

Downstream raw materials:

ethyl 3,4,6,7-tetra-O-benzyl-1-thio-L-glycero-α-D-manno-heptopyranoside

6-O-(2-O-Acetyl-3,4,6,7-tetra-O-benzyl-L-glycero-α-D-manno-heptopyranosyl)-1,2:3,4-di-O-isopropyliden-α-D-galactopyranosid

(2S,4R,5R,6R)-5-[(2S,3S,4S,5S,6R)-3-Acetoxy-4,5-bis-benzyloxy-6-((S)-1,2-bis-benzyloxy-ethyl)-tetrahydro-pyran-2-yloxy]-4-benzyloxy-6-((R)-1,2-dihydroxy-ethyl)-2-methoxy-tetrahydro-pyran-2-carboxylic acid methyl ester

Methyl-onat

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 116302-70-6 2-O-Acetyl-3,4,6,7-tetra-O-benzyl-L-glycero-α-D-manno-heptopyranosylchlorid

Send

Send

Metric Ton KG G Pound L ML

Send

Send